Recovery and outcomes after the acute respiratory distress syndrome (ARDS) in patients and their family caregivers

Margaret S. Herridge, Marc Moss, Catherine L. Hough, Ramona O. Hopkins, Todd W. Rice, O. Joseph Bienvenu, Elie Azoulay

Research output: Contribution to journalReview articlepeer-review

Abstract

Outcomes after acute respiratory distress syndrome (ARDS) are similar to those of other survivors of critical illness and largely affect the nerve, muscle, and central nervous system but also include a constellation of varied physical devastations ranging from contractures and frozen joints to tooth loss and cosmesis. Compromised quality of life is related to a spectrum of impairment of physical, social, emotional, and neurocognitive function and to a much lesser extent discrete pulmonary disability. Intensive care unit-acquired weakness (ICUAW) is ubiquitous and includes contributions from both critical illness polyneuropathy and myopathy, and recovery from these lesions may be incomplete at 5 years after ICU discharge. Cognitive impairment in ARDS survivors ranges from 70 to 100 % at hospital discharge, 46 to 80 % at 1 year, and 20 % at 5 years, and mood disorders including depression and post-traumatic stress disorder (PTSD) are also sustained and prevalent. Robust multidisciplinary and longitudinal interventions that improve these outcomes are still uncertain and data in our literature are conflicting. Studies are needed in family members of ARDS survivors to better understand long-term outcomes of the post-ICU family syndrome and to evaluate how it affects patient recovery.

Original languageEnglish (US)
Pages (from-to)725-738
Number of pages14
JournalIntensive Care Medicine
Volume42
Issue number5
DOIs
StatePublished - May 1 2016

Keywords

  • Acute respiratory distress syndrome (ARDS)
  • Cost
  • Healthcare utilization
  • ICU acquired weakness
  • Neuropsychological
  • Outcome

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

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