Reconstruction of in-vivo optical properties for human prostate using interstitial diffuse optical tomography

Ken Kang Hsin Wang, Timothy C. Zhu

Research output: Contribution to journalArticle


A CW interstitial diffuse optical tomography has been developed to characterize the in-vivo optical properties of prostate gland during photodynamic therapy. The spatial distributions of light fluence rate can be described by the diffusion equation. Optical properties of the prostate are reconstructed by solving the inverse problem with an adjoint method. The 3D reconstructed in-vivo optical properties for a human prostate is illustrated and compared with the results generated by a well-established point-by-point method. Moreover, the calculated fluence rate using the reconstructed optical properties matches the measured data.

Original languageEnglish (US)
Pages (from-to)11665-11672
Number of pages8
JournalOptics Express
Issue number14
StatePublished - Jul 6 2009



  • (170.3880) Medical and biological imaging
  • (170.5180) Photodynamic therapy
  • (170.7230) Urology
  • 170.6960 (tomography)

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

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