Reconstructing smell

Robert D. Barber, Gabriele V. Ronnett

Research output: Contribution to journalArticlepeer-review

Abstract

Odorant signal transduction and neurogenesis are fundamental properties of the olfactory epithelium. Many preparations have been used to elucidate some of the mechanisms underlying these properties. In this article, we briefly review these research areas and describe some of the techniques used to obtain the data. We focus specifically on the cell-culture paradigm and the data obtained from various immortal cell lines in their attempts to reconstruct the olfactory epithelium in vitro.

Original languageEnglish (US)
Pages (from-to)161-173
Number of pages13
JournalMolecular Neurobiology
Volume21
Issue number3
DOIs
StatePublished - 2000

Keywords

  • Cell culture
  • Cell lines
  • Neurogenesis
  • Odorant receptor
  • Olfactory epithelium
  • Olfactory receptor neuron

ASJC Scopus subject areas

  • Neuroscience(all)
  • Physiology

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