Recognizing Seizures and Epilepsy: Insights from Pathophysiology

Research output: Chapter in Book/Report/Conference proceedingChapter


This chapter provides a brief overview of seizures and epilepsy, with emphasis on the pathophysiological mechanisms that determine seizure generation. Seizure classification is reviewed in relation to underlying mechanisms. A discussion of paroxysmal neurologic events that mimic seizures provides a comparison of the various pathophysiological mechanisms in seizures compared to seizure mimics. Emerging knowledge of genetic epilepsies and mechanisms of antiepileptic drug action emphasize the importance of understanding the pathophysiology of seizures in clinical practice. The concepts presented here provide a context for subsequent chapters in this book.

Original languageEnglish (US)
Title of host publicationEpilepsy
Number of pages9
ISBN (Electronic)9781118456989
ISBN (Print)9781118456941
StatePublished - Mar 17 2014
Externally publishedYes


  • Antiepileptic drug
  • Epilepsy
  • Pathophysiology
  • Seizure
  • Seizure mimics

ASJC Scopus subject areas

  • Medicine(all)

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