Receptor-ligand binding: 'Catch' bonds finally caught

Research output: Contribution to journalReview article

Abstract

Leukocyte recruitment to sites of inflammation is initiated by the selectin family of adhesion receptors. Recent research reveals that P-selectin binding to its ligand exhibits 'catch' to 'slip' bond transition that may help explain the shear threshold phenomenon.

Original languageEnglish (US)
Pages (from-to)R611-R613
JournalCurrent Biology
Volume13
Issue number15
DOIs
StatePublished - Aug 5 2003

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

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