Recent Advances in Necrotizing Enterocolitis Research: Strategies for Implementation in Clinical Practice

Mohan Pammi; Isabelle G. De Plaen; Akhil Maheshwari

doi:10.1016/j.clp.2020.02.011

Recent Advances in Necrotizing Enterocolitis Research: Strategies for Implementation in Clinical Practice

Mohan Pammi, Isabelle G. De Plaen, Akhil Maheshwari

School of Medicine

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Abstract

Necrotizing enterocolitis (NEC) is a complex inflammatory necrosis of the neonatal intestine, which is likely to require a multipronged approach for prevention and treatment. Despite identifying and defining NEC as a disease entity several decades back, no major progress has been made toward its early identification, treatment, or prevention. This article reviews the latest research strategies that are currently ongoing for early diagnosis and monitoring and prevention of the disease.

Original language	English (US)
Pages (from-to)	383-397
Number of pages	15
Journal	Clinics in Perinatology
Volume	47
Issue number	2
DOIs	https://doi.org/10.1016/j.clp.2020.02.011
State	Published - Jun 2020

Keywords

NEC
Necrotizing enterocolitis
Neonate
Preterm
Research
Strategies

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Obstetrics and Gynecology

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10.1016/j.clp.2020.02.011

Cite this

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title = "Recent Advances in Necrotizing Enterocolitis Research: Strategies for Implementation in Clinical Practice",

abstract = "Necrotizing enterocolitis (NEC) is a complex inflammatory necrosis of the neonatal intestine, which is likely to require a multipronged approach for prevention and treatment. Despite identifying and defining NEC as a disease entity several decades back, no major progress has been made toward its early identification, treatment, or prevention. This article reviews the latest research strategies that are currently ongoing for early diagnosis and monitoring and prevention of the disease.",

keywords = "NEC, Necrotizing enterocolitis, Neonate, Preterm, Research, Strategies",

author = "Mohan Pammi and {De Plaen}, {Isabelle G.} and Akhil Maheshwari",

note = "Funding Information: Funding: NIH awards DK116568 (to I.G. De Plaen) and HL124078, HL133022 (to A. Maheshwari). Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",

year = "2020",

month = jun,

doi = "10.1016/j.clp.2020.02.011",

language = "English (US)",

volume = "47",

pages = "383--397",

journal = "Clinics in Perinatology",

issn = "0095-5108",

publisher = "W.B. Saunders Ltd",

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T1 - Recent Advances in Necrotizing Enterocolitis Research

T2 - Strategies for Implementation in Clinical Practice

AU - Pammi, Mohan

AU - De Plaen, Isabelle G.

AU - Maheshwari, Akhil

PY - 2020/6

Y1 - 2020/6

N2 - Necrotizing enterocolitis (NEC) is a complex inflammatory necrosis of the neonatal intestine, which is likely to require a multipronged approach for prevention and treatment. Despite identifying and defining NEC as a disease entity several decades back, no major progress has been made toward its early identification, treatment, or prevention. This article reviews the latest research strategies that are currently ongoing for early diagnosis and monitoring and prevention of the disease.

AB - Necrotizing enterocolitis (NEC) is a complex inflammatory necrosis of the neonatal intestine, which is likely to require a multipronged approach for prevention and treatment. Despite identifying and defining NEC as a disease entity several decades back, no major progress has been made toward its early identification, treatment, or prevention. This article reviews the latest research strategies that are currently ongoing for early diagnosis and monitoring and prevention of the disease.

KW - NEC

KW - Necrotizing enterocolitis

KW - Neonate

KW - Preterm

KW - Research

KW - Strategies

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U2 - 10.1016/j.clp.2020.02.011

DO - 10.1016/j.clp.2020.02.011

M3 - Review article

C2 - 32439118

AN - SCOPUS:85082922258

SN - 0095-5108

VL - 47

SP - 383

EP - 397

JO - Clinics in Perinatology

JF - Clinics in Perinatology

IS - 2

ER -

Recent Advances in Necrotizing Enterocolitis Research: Strategies for Implementation in Clinical Practice

Abstract

Keywords

ASJC Scopus subject areas

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