Recent advances in cyclic-adenosine monophosphate/protein kinase A signaling in ethanol-induced synaptic and behavioral alterations

L. Judson Chandler, Antonello Bonci, Gary S. Wand, Richard A. Morrisett

Research output: Contribution to journalArticle

Abstract

This article represents the proceedings of a symposium at the 2002 RSA Meeting in San Francisco, California, organized and co-chaired by L. Judson Chandler and Richard A. Morrisett. The presentations were (1) PKA regulates chronic ethanol-induced synaptic targeting of NMDA receptors, by L. Judson Chandler; (2) Long-lasting potentiation of GABAergic synapses in dopamine neurons after a single in vivo ethanol exposure, by Antonello Bonci; (3) The DARPP-32 cascade and regulation of the ethanol sensitivity of NMDA receptors in the nucleus accumbens, by Richard A. Morrisett; (4) and The cAMP/PKA signal transduction pathway modulates ethanol consumption and sedative effects of ethanol, by Gary S. Wand.

Original languageEnglish (US)
Pages (from-to)1129-1136
Number of pages8
JournalAlcoholism: Clinical and Experimental Research
Volume28
Issue number7
DOIs
StatePublished - Jul 2004

Keywords

  • Cyclic Adenosine Monophosphate
  • DARPP-32
  • Dopamine
  • Ethanol
  • NMDA Receptors
  • Nucleus Accumbens
  • Protein Kinase A
  • Ventral Tegmental Area

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Toxicology
  • Psychiatry and Mental health

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