Recanalization and Remarkable Outcome after Subocclusive Thrombus: A Case Report

Sarah Nelson, David Y. Chung, Guy Rordorf

Research output: Contribution to journalArticle

Abstract

Minimal literature exists regarding subocclusive thrombi and their management in acute ischemic stroke, and no randomized trials or guidelines are currently available. We present the case of an 83-year-old man with multiple vascular risk factors and recent cardiac surgery who presented with a severe left middle cerebral artery (MCA) syndrome due to a subocclusive thrombus. Intravenous (IV) tissue plasminogen activator was contraindicated given the patient's recent surgery, and endovascular therapy was deferred given improvement in symptoms. He was placed on IV heparin. His symptoms improved with recanalization of the MCA. Optimal management of subocclusive thrombi, which appear to have better outcomes than occlusive thrombi, has yet to be elucidated. Acute anticoagulation and endovascular therapy may both be reasonable; however, there are minimal data supporting the use of either and further studies are needed to develop the most favorable treatment algorithm. In the meantime, management decisions should be made on a case-by-case basis by multidisciplinary care teams.

Original languageEnglish (US)
Pages (from-to)e28-e30
JournalJournal of Stroke and Cerebrovascular Diseases
Volume25
Issue number3
DOIs
StatePublished - Mar 1 2016
Externally publishedYes

Fingerprint

Thrombosis
Middle Cerebral Artery Infarction
Middle Cerebral Artery
Tissue Plasminogen Activator
Thoracic Surgery
Heparin
Therapeutics
Stroke
Guidelines

Keywords

  • Acute ischemic stroke
  • anticoagulation
  • computed tomography
  • endovascular therapy
  • intraluminal thrombus
  • subocclusive thrombus

ASJC Scopus subject areas

  • Surgery
  • Rehabilitation
  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine

Cite this

Recanalization and Remarkable Outcome after Subocclusive Thrombus : A Case Report. / Nelson, Sarah; Chung, David Y.; Rordorf, Guy.

In: Journal of Stroke and Cerebrovascular Diseases, Vol. 25, No. 3, 01.03.2016, p. e28-e30.

Research output: Contribution to journalArticle

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