Real-Time Magnetic Resonance Imaging Guidance Improves the Diagnostic Yield of Endomyocardial Biopsy

Toby Rogers, Kanishka Ratnayaka, Parag Perry Karmarkar, Adrienne E. Campbell-Washburn, William H. Schenke, Jonathan R. Mazal, Ozgur Kocaturk, Anthony Z. Faranesh, Robert J. Lederman

Research output: Contribution to journalArticle

Abstract

Diagnostic yield of endomyocardial biopsy is low, particularly in disease that affects the myocardium in a nonuniform distribution. The authors hypothesized that real-time MRI guidance could improve the yield through targeted biopsy of focal myocardial pathology. They tested this hypothesis in an animal model of focal myocardial pathology using intracoronary ethanol and microspheres. The authors compared real-time MRI-guided endomyocardial biopsy in swine using a custom actively visualized MRI bioptome against x-ray–guided biopsy using a commercial bioptome by skilled operators. Real-time MRI guidance significantly increased the diagnostic yield of endomyocardial biopsy.

Original languageEnglish (US)
Pages (from-to)376-383
Number of pages8
JournalJACC: Basic to Translational Science
Volume1
Issue number5
DOIs
StatePublished - Aug 1 2016
Externally publishedYes

Fingerprint

Magnetic Resonance Imaging
Biopsy
Pathology
Microspheres
Myocardium
Ethanol
Swine
Animal Models

Keywords

  • endomyocardial biopsy
  • heart failure
  • interventional cardiovascular magnetic resonance imaging
  • myocarditis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Real-Time Magnetic Resonance Imaging Guidance Improves the Diagnostic Yield of Endomyocardial Biopsy. / Rogers, Toby; Ratnayaka, Kanishka; Karmarkar, Parag Perry; Campbell-Washburn, Adrienne E.; Schenke, William H.; Mazal, Jonathan R.; Kocaturk, Ozgur; Faranesh, Anthony Z.; Lederman, Robert J.

In: JACC: Basic to Translational Science, Vol. 1, No. 5, 01.08.2016, p. 376-383.

Research output: Contribution to journalArticle

Rogers, T, Ratnayaka, K, Karmarkar, PP, Campbell-Washburn, AE, Schenke, WH, Mazal, JR, Kocaturk, O, Faranesh, AZ & Lederman, RJ 2016, 'Real-Time Magnetic Resonance Imaging Guidance Improves the Diagnostic Yield of Endomyocardial Biopsy', JACC: Basic to Translational Science, vol. 1, no. 5, pp. 376-383. https://doi.org/10.1016/j.jacbts.2016.05.007
Rogers, Toby ; Ratnayaka, Kanishka ; Karmarkar, Parag Perry ; Campbell-Washburn, Adrienne E. ; Schenke, William H. ; Mazal, Jonathan R. ; Kocaturk, Ozgur ; Faranesh, Anthony Z. ; Lederman, Robert J. / Real-Time Magnetic Resonance Imaging Guidance Improves the Diagnostic Yield of Endomyocardial Biopsy. In: JACC: Basic to Translational Science. 2016 ; Vol. 1, No. 5. pp. 376-383.
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