Real-time fast strain-encoded magnetic resonance imaging to evaluate regional myocardial function at 3.0 Tesla: Comparison to conventional tagging

Grigorios Korosoglou, Amr A. Youssef, Kenneth C. Bilchick, El Sayed Ibrahim, Albert C. Lardo, Shenghan Lai, Nael F. Osman

Research output: Contribution to journalArticle

Abstract

Purpose: To compare the utility of the real-time technique fast strain-encoded magnetic resonance imaging (fast-SENC) for the quantification of regional myocardial function to conventional tagged magnetic resonance imaging (MRI). Materials and Methods: Healthy volunteers (N = 12) and patients with heart failure (N = 7) were examined using tagged MRI and fast-SENC at 3.0T. Circumferential strain was measured using fast-SENC in six endo- and six subepicardial regions in the basal-, mid-, and apical-septum and the basal-, mid-, and apical-lateral wall from the four-chamber view. These measurements were plotted to tagging, in corresponding myocardial segments. Results: Peak systolic strain (Ecc) and early diastolic strain rate (Ecc/second) acquired by fast-SENC correlated closely to tagged MRI (r = 0.90 for Ecc and r = 0.91 for Ecc/second, P < 0.001 for both). Both fast-SENC and tagging identified differences in regional systolic and diastolic function between normal myocardium and dysfunctional segments in patients with heart failure (for fast-SENC: Ecc = -21.7 ± 2.7 in healthy volunteers vs. -12.8 ± 4.2 in hypokinetic vs. 0.6 ± 3.8 in akinetic/dyskinetic segments, P < 0.001 between all; Ecc/second = 104 ± 20/second in healthy volunteers vs. 37 ± 9/second in hypokinetic vs. -16 ± 15/second in akinetic/dyskinetic segments, P < 0.001 between all). Quantitative analysis was more time-consuming for conventional tagging than for fast-SENC (time-spent of 3.8 ± 0.7 minutes vs. 9.5 ± 0.7 minutes per patient, P < 0.001). Conclusion: Fast-SENC allows the rapid and accurate quantification of regional myocardial function. The information derived from fast-SENC during a single heartbeat seems to be superior or equal to that acquired by conventional tagging during several heart cycles and prolonged breathholds.

Original languageEnglish (US)
Pages (from-to)1012-1018
Number of pages7
JournalJournal of Magnetic Resonance Imaging
Volume27
Issue number5
DOIs
StatePublished - May 1 2008

    Fingerprint

Keywords

  • Diastolic function
  • Fast-SENC
  • Magnetic resonance imaging
  • Myocardial strain
  • Myocardial tagging

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this