Real-time fast strain-encoded magnetic resonance imaging to evaluate regional myocardial function at 3.0 Tesla

Comparison to conventional tagging

Grigorios Korosoglou, Amr A. Youssef, Kenneth C. Bilchick, El Sayed Ibrahim, Albert C. Lardo, Shenghan Lai, Nael Fakhry Osman

Research output: Contribution to journalArticle

Abstract

Purpose: To compare the utility of the real-time technique fast strain-encoded magnetic resonance imaging (fast-SENC) for the quantification of regional myocardial function to conventional tagged magnetic resonance imaging (MRI). Materials and Methods: Healthy volunteers (N = 12) and patients with heart failure (N = 7) were examined using tagged MRI and fast-SENC at 3.0T. Circumferential strain was measured using fast-SENC in six endo- and six subepicardial regions in the basal-, mid-, and apical-septum and the basal-, mid-, and apical-lateral wall from the four-chamber view. These measurements were plotted to tagging, in corresponding myocardial segments. Results: Peak systolic strain (Ecc) and early diastolic strain rate (Ecc/second) acquired by fast-SENC correlated closely to tagged MRI (r = 0.90 for Ecc and r = 0.91 for Ecc/second, P <0.001 for both). Both fast-SENC and tagging identified differences in regional systolic and diastolic function between normal myocardium and dysfunctional segments in patients with heart failure (for fast-SENC: Ecc = -21.7 ± 2.7 in healthy volunteers vs. -12.8 ± 4.2 in hypokinetic vs. 0.6 ± 3.8 in akinetic/dyskinetic segments, P <0.001 between all; Ecc/second = 104 ± 20/second in healthy volunteers vs. 37 ± 9/second in hypokinetic vs. -16 ± 15/second in akinetic/dyskinetic segments, P <0.001 between all). Quantitative analysis was more time-consuming for conventional tagging than for fast-SENC (time-spent of 3.8 ± 0.7 minutes vs. 9.5 ± 0.7 minutes per patient, P <0.001). Conclusion: Fast-SENC allows the rapid and accurate quantification of regional myocardial function. The information derived from fast-SENC during a single heartbeat seems to be superior or equal to that acquired by conventional tagging during several heart cycles and prolonged breathholds.

Original languageEnglish (US)
Pages (from-to)1012-1018
Number of pages7
JournalJournal of Magnetic Resonance Imaging
Volume27
Issue number5
DOIs
StatePublished - May 2008

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Magnetic Resonance Imaging
Healthy Volunteers
Heart Failure
Myocardium

Keywords

  • Diastolic function
  • Fast-SENC
  • Magnetic resonance imaging
  • Myocardial strain
  • Myocardial tagging

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Real-time fast strain-encoded magnetic resonance imaging to evaluate regional myocardial function at 3.0 Tesla : Comparison to conventional tagging. / Korosoglou, Grigorios; Youssef, Amr A.; Bilchick, Kenneth C.; Ibrahim, El Sayed; Lardo, Albert C.; Lai, Shenghan; Osman, Nael Fakhry.

In: Journal of Magnetic Resonance Imaging, Vol. 27, No. 5, 05.2008, p. 1012-1018.

Research output: Contribution to journalArticle

Korosoglou, Grigorios ; Youssef, Amr A. ; Bilchick, Kenneth C. ; Ibrahim, El Sayed ; Lardo, Albert C. ; Lai, Shenghan ; Osman, Nael Fakhry. / Real-time fast strain-encoded magnetic resonance imaging to evaluate regional myocardial function at 3.0 Tesla : Comparison to conventional tagging. In: Journal of Magnetic Resonance Imaging. 2008 ; Vol. 27, No. 5. pp. 1012-1018.
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abstract = "Purpose: To compare the utility of the real-time technique fast strain-encoded magnetic resonance imaging (fast-SENC) for the quantification of regional myocardial function to conventional tagged magnetic resonance imaging (MRI). Materials and Methods: Healthy volunteers (N = 12) and patients with heart failure (N = 7) were examined using tagged MRI and fast-SENC at 3.0T. Circumferential strain was measured using fast-SENC in six endo- and six subepicardial regions in the basal-, mid-, and apical-septum and the basal-, mid-, and apical-lateral wall from the four-chamber view. These measurements were plotted to tagging, in corresponding myocardial segments. Results: Peak systolic strain (Ecc) and early diastolic strain rate (Ecc/second) acquired by fast-SENC correlated closely to tagged MRI (r = 0.90 for Ecc and r = 0.91 for Ecc/second, P <0.001 for both). Both fast-SENC and tagging identified differences in regional systolic and diastolic function between normal myocardium and dysfunctional segments in patients with heart failure (for fast-SENC: Ecc = -21.7 ± 2.7 in healthy volunteers vs. -12.8 ± 4.2 in hypokinetic vs. 0.6 ± 3.8 in akinetic/dyskinetic segments, P <0.001 between all; Ecc/second = 104 ± 20/second in healthy volunteers vs. 37 ± 9/second in hypokinetic vs. -16 ± 15/second in akinetic/dyskinetic segments, P <0.001 between all). Quantitative analysis was more time-consuming for conventional tagging than for fast-SENC (time-spent of 3.8 ± 0.7 minutes vs. 9.5 ± 0.7 minutes per patient, P <0.001). Conclusion: Fast-SENC allows the rapid and accurate quantification of regional myocardial function. The information derived from fast-SENC during a single heartbeat seems to be superior or equal to that acquired by conventional tagging during several heart cycles and prolonged breathholds.",
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T1 - Real-time fast strain-encoded magnetic resonance imaging to evaluate regional myocardial function at 3.0 Tesla

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AU - Korosoglou, Grigorios

AU - Youssef, Amr A.

AU - Bilchick, Kenneth C.

AU - Ibrahim, El Sayed

AU - Lardo, Albert C.

AU - Lai, Shenghan

AU - Osman, Nael Fakhry

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N2 - Purpose: To compare the utility of the real-time technique fast strain-encoded magnetic resonance imaging (fast-SENC) for the quantification of regional myocardial function to conventional tagged magnetic resonance imaging (MRI). Materials and Methods: Healthy volunteers (N = 12) and patients with heart failure (N = 7) were examined using tagged MRI and fast-SENC at 3.0T. Circumferential strain was measured using fast-SENC in six endo- and six subepicardial regions in the basal-, mid-, and apical-septum and the basal-, mid-, and apical-lateral wall from the four-chamber view. These measurements were plotted to tagging, in corresponding myocardial segments. Results: Peak systolic strain (Ecc) and early diastolic strain rate (Ecc/second) acquired by fast-SENC correlated closely to tagged MRI (r = 0.90 for Ecc and r = 0.91 for Ecc/second, P <0.001 for both). Both fast-SENC and tagging identified differences in regional systolic and diastolic function between normal myocardium and dysfunctional segments in patients with heart failure (for fast-SENC: Ecc = -21.7 ± 2.7 in healthy volunteers vs. -12.8 ± 4.2 in hypokinetic vs. 0.6 ± 3.8 in akinetic/dyskinetic segments, P <0.001 between all; Ecc/second = 104 ± 20/second in healthy volunteers vs. 37 ± 9/second in hypokinetic vs. -16 ± 15/second in akinetic/dyskinetic segments, P <0.001 between all). Quantitative analysis was more time-consuming for conventional tagging than for fast-SENC (time-spent of 3.8 ± 0.7 minutes vs. 9.5 ± 0.7 minutes per patient, P <0.001). Conclusion: Fast-SENC allows the rapid and accurate quantification of regional myocardial function. The information derived from fast-SENC during a single heartbeat seems to be superior or equal to that acquired by conventional tagging during several heart cycles and prolonged breathholds.

AB - Purpose: To compare the utility of the real-time technique fast strain-encoded magnetic resonance imaging (fast-SENC) for the quantification of regional myocardial function to conventional tagged magnetic resonance imaging (MRI). Materials and Methods: Healthy volunteers (N = 12) and patients with heart failure (N = 7) were examined using tagged MRI and fast-SENC at 3.0T. Circumferential strain was measured using fast-SENC in six endo- and six subepicardial regions in the basal-, mid-, and apical-septum and the basal-, mid-, and apical-lateral wall from the four-chamber view. These measurements were plotted to tagging, in corresponding myocardial segments. Results: Peak systolic strain (Ecc) and early diastolic strain rate (Ecc/second) acquired by fast-SENC correlated closely to tagged MRI (r = 0.90 for Ecc and r = 0.91 for Ecc/second, P <0.001 for both). Both fast-SENC and tagging identified differences in regional systolic and diastolic function between normal myocardium and dysfunctional segments in patients with heart failure (for fast-SENC: Ecc = -21.7 ± 2.7 in healthy volunteers vs. -12.8 ± 4.2 in hypokinetic vs. 0.6 ± 3.8 in akinetic/dyskinetic segments, P <0.001 between all; Ecc/second = 104 ± 20/second in healthy volunteers vs. 37 ± 9/second in hypokinetic vs. -16 ± 15/second in akinetic/dyskinetic segments, P <0.001 between all). Quantitative analysis was more time-consuming for conventional tagging than for fast-SENC (time-spent of 3.8 ± 0.7 minutes vs. 9.5 ± 0.7 minutes per patient, P <0.001). Conclusion: Fast-SENC allows the rapid and accurate quantification of regional myocardial function. The information derived from fast-SENC during a single heartbeat seems to be superior or equal to that acquired by conventional tagging during several heart cycles and prolonged breathholds.

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KW - Myocardial tagging

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