Real-time 3D fluoroscopy-guided large core needle biopsy of renal masses: A critical early evaluation according to the IDEAL recommendations

Maurice A A J Van Den Bosch, Stephanie G C Kroeze, Merel Huisman, Helena M. Verkooijen, J. L H Ruud Bosch, Paul J. Van Diest

Research output: Contribution to journalArticle

Abstract

Introduction Three-dimensional (3D) real-time fluoroscopy cone beam CT is a promising new technique for image-guided biopsy of solid tumors. We evaluated the technical feasibility, diagnostic accuracy, and complications of this technique for guidance of large-core needle biopsy in patients with suspicious renal masses. Methods Thirteen patients with 13 suspicious renal masses underwent large-core needle biopsy under 3D realtime fluoroscopy cone beam CT guidance. Imaging acquisition and subsequent 3D reconstruction was done by a mobile flat-panel detector (FD) C-arm system to plan the needle path. Large-core needle biopsies were taken by the interventional radiologist. Technical success, accuracy, and safety were evaluated according to the Innovation, Development, Exploration, Assessment, Long-term study (IDEAL) recommendations. Results Median tumor size was 2.6 (range, 1.0-14.0) cm. In ten (77%) patients, the histological diagnosis corresponded to the imaging findings: five were malignancies, five benign lesions. Technical feasibility was 77% (10/13); in three patients biopsy results were inconclusive. The lesion size of these three patients was

Original languageEnglish (US)
Pages (from-to)680-685
Number of pages6
JournalCardioVascular and Interventional Radiology
Volume35
Issue number3
DOIs
StatePublished - Jun 2012
Externally publishedYes

Keywords

  • Biopsy
  • Cone beam computed tomography
  • IDEAL
  • Needle guidance
  • Real-time imaging
  • Renal masses

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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