Reading within the lines: Naturally processed peptides displayed by MHC class I molecules

Nilabh Shastri, Thomas Serwold, Pedro Paz

Research output: Contribution to journalArticlepeer-review

Abstract

A typical mammalian cell contains tens of thousands of different gene products. Snippets of this genetic information are displayed on the cell surface by MHC class I molecules as short peptides for immune surveillance by CD8+ T lymphocytes. Genetic and biochemical analysis of these peptides is revealing novel sources and mechanisms by which these peptide/MHC class I complexes arise.

Original languageEnglish (US)
Pages (from-to)137-144
Number of pages8
JournalCurrent Opinion in Immunology
Volume10
Issue number2
DOIs
StatePublished - Apr 1998
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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