The reaction of hemoglobin with nitric oxide has been investigated by recording absorbtion spectra of human hemoglobin in time, in the presence of different ligands. The results are summarized in the figure. They suggest that the combination of the various derivatives of hemoglobin with NO would converge to the formation of methemoglobin [Hb(III)], establishing a redox cycle which depletes the nitric oxide being produced.
|Original language||English (US)|
|Journal||Artificial Cells, Blood Substitutes, and Immobilization Biotechnology|
|State||Published - Nov 1 1994|
|Event||Proceedings of the 11th Congress of the International Society for Artificial Cells, Blood Substitutes and Immobilization Biotechnology, (ISABI) - Boston, MA, USA|
Duration: Jul 24 1994 → Jul 27 1994
ASJC Scopus subject areas
- Biomedical Engineering