In 1862, Maurice Raynaud published his medical school thesis in which he argued that some people have transient digital ischemia when exposed to cold temperatures. It is now recognized that skin blood flow in humans provides an important mechanism for normal thermoregulation. In fact, a normal response to cold exposure is vasoconstriction of the cutaneous blood vessels, leading to a decrease in heat loss from the body and protection against hypothermia .
|Original language||English (US)|
|Title of host publication||Sjogren's Syndrome|
|Subtitle of host publication||Diagnosis and Therapeutics|
|Publisher||Springer-Verlag London Ltd|
|Number of pages||17|
|State||Published - Jan 1 2012|
ASJC Scopus subject areas