Rational use of antibiotics for perforated appendicitis in childhood

Irving B. David, James R. Buck, Robert M. Filler

Research output: Contribution to journalArticle

Abstract

Gangrenous and perforated appendicitis was reviewed in 300 pediatric patients. Those with only gangrene generally had a benign course regardless of whether antibiotic therapy was used. However, patients with local perforation or generalized peritonitis had a high incidence of infective complications if they were not treated with antibiotics. Children treated with ampicillin, gentamicin, and clindamycin had markedly fewer wound infections and abscesses and were able to tolerate a diet and go home sooner than those receiving ampicillin and/or gentamicin.

Original languageEnglish (US)
Pages (from-to)494-500
Number of pages7
JournalJournal of Pediatric Surgery
Volume17
Issue number5
DOIs
StatePublished - 1982
Externally publishedYes

Fingerprint

Appendicitis
Ampicillin
Gentamicins
Anti-Bacterial Agents
Gangrene
Clindamycin
Wound Infection
Peritonitis
Abscess
Pediatrics
Diet
Incidence
Therapeutics

Keywords

  • Appendicitis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Surgery

Cite this

Rational use of antibiotics for perforated appendicitis in childhood. / David, Irving B.; Buck, James R.; Filler, Robert M.

In: Journal of Pediatric Surgery, Vol. 17, No. 5, 1982, p. 494-500.

Research output: Contribution to journalArticle

David, Irving B. ; Buck, James R. ; Filler, Robert M. / Rational use of antibiotics for perforated appendicitis in childhood. In: Journal of Pediatric Surgery. 1982 ; Vol. 17, No. 5. pp. 494-500.
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