Rates and cost of hospitalization before and after initiation of antiretroviral therapy in urban and rural settings in South Africa

Gesine Meyer-Rath, Alana T. Brennan, Matthew P. Fox, Tebogo Modisenyane, Nkeko Tshabangu, Lerato Mohapi, Sydney Rosen, Neil Martinson

Research output: Contribution to journalArticle

Abstract

Few studies have compared hospitalizations before and after antiretroviral therapy (ART) initiation in the same patients. We analyzed the cost of hospitalizations among 3906 adult patients in 2 South African hospitals, 30% of whom initiated ART. Hospitalizations were 50% and 40% more frequent and 1.5 and 2.6 times more costly at a CD4 cell count ,100 cells/mm3 when compared with 200-350 cells/mm3 in the pre-ART and ART period, respectively. Mean inpatient cost per patient year was USD 117 (95% confidence interval, 85 to 158) for patients on ART and USD 72 (95% confidence interval, 56 to 89) for pre-ART patients. Raising ART eligibility thresholds could avoid the high cost of hospitalization before and immediately after ART initiation.

Original languageEnglish (US)
Pages (from-to)322-328
Number of pages7
JournalJournal of Acquired Immune Deficiency Syndromes
Volume62
Issue number3
DOIs
StatePublished - Mar 1 2013

Keywords

  • Admission
  • Hospitalization
  • Inpatient
  • Pre-ART
  • Resource-limited setting

ASJC Scopus subject areas

  • Infectious Diseases
  • Pharmacology (medical)

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