Abstract
Much current neuropharmacological research describes drug site of action and effect in terms of rotational behavior in rats. Such studies at the National Institutes of Health led to the development of required instrumentation capabilities. The method developed for quantifying rotational behavior to the exclusion of other locomotor activity is presented. Such full turns counts can be output as mechanical counter inputs, computer inputs, user-selected time interval subtotals, summary totals, or a voltage proportional to cumulative count which provides turning-rate data when recorded on strip-chart. The latter two options are described herein.
Original language | English (US) |
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Pages (from-to) | 433-436 |
Number of pages | 4 |
Journal | Pharmacology, Biochemistry and Behavior |
Volume | 10 |
Issue number | 3 |
DOIs | |
State | Published - Mar 1979 |
Externally published | Yes |
Keywords
- Circling behavior
- Rotation
- Rotometer
ASJC Scopus subject areas
- Biochemistry
- Toxicology
- Pharmacology
- Clinical Biochemistry
- Biological Psychiatry
- Behavioral Neuroscience