Rare tumors: Retinoblastoma, nasopharyngeal cancer, and adrenocorticoid tumors

Samir Patel, Jennifer Vogel, Kristin Bradley, Paul J. Chuba, Jeffrey Buchsbaum, Matthew J. Krasin

Research output: Contribution to journalArticlepeer-review

Abstract

The role of surgery, chemotherapy, and radiation therapy for retinoblastoma has evolved considerably over the years with the efficacy of intraarterial chemotherapy and the high incidence of secondary malignant neoplasms following radiation therapy. The use of spot scanning intensity-modulated proton therapy may reduce the risk of secondary malignancies. For pediatric nasopharyngeal carcinoma, the current standard of care is induction chemotherapy followed by chemoradiation therapy. For adrenocortical carcinoma, the mainstay of treatment is surgery and chemotherapy. The role of radiation therapy remains to be defined.

Original languageEnglish (US)
Article numbere28253
JournalPediatric Blood and Cancer
Volume68
Issue numberS2
DOIs
StatePublished - May 2021

Keywords

  • adrenocorticoid tumors
  • chemotherapy
  • nasopharyngeal carcinoma
  • radiation therapy
  • retinoblastoma
  • surgery

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology

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