TY - JOUR
T1 - Rare tumors in children
T2 - Progress through collaboration
AU - Pappo, Alberto S.
AU - Furman, Wayne L.
AU - Schultz, Kris A.
AU - Ferrari, Andrea
AU - Helman, Lee
AU - Krailo, Mark D.
N1 - Publisher Copyright:
© 2015 by American Society of Clinical Oncology.
PY - 2015/9/20
Y1 - 2015/9/20
N2 - Rare pediatric tumors account for approximately 10% of all childhood cancers, which in themselves are a rare entity. The diverse histologies and clinical behaviors of rare pediatric tumors pose challenges to the investigation of their biologic and clinical features. National and international cooperative groups such as the Rare Tumor Committee of the Children's Oncology Group, Rare Tumors in Pediatric Age Project, and European Cooperative Study Group for Pediatric Rare Tumors have developed several initiatives to advance knowledge about rare pediatric cancers. However, these programs have been only partially effective, necessitating the development of alternative mechanisms to study these challenging diseases. In this article, we review the current national and international collaborative strategies to study rare pediatric cancers and alternative methods under exploration to enhance those efforts, such as independent registries and disease-specific, National Cancer Institute-sponsored clinics.
AB - Rare pediatric tumors account for approximately 10% of all childhood cancers, which in themselves are a rare entity. The diverse histologies and clinical behaviors of rare pediatric tumors pose challenges to the investigation of their biologic and clinical features. National and international cooperative groups such as the Rare Tumor Committee of the Children's Oncology Group, Rare Tumors in Pediatric Age Project, and European Cooperative Study Group for Pediatric Rare Tumors have developed several initiatives to advance knowledge about rare pediatric cancers. However, these programs have been only partially effective, necessitating the development of alternative mechanisms to study these challenging diseases. In this article, we review the current national and international collaborative strategies to study rare pediatric cancers and alternative methods under exploration to enhance those efforts, such as independent registries and disease-specific, National Cancer Institute-sponsored clinics.
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U2 - 10.1200/JCO.2014.59.3632
DO - 10.1200/JCO.2014.59.3632
M3 - Review article
C2 - 26304909
AN - SCOPUS:84942236059
VL - 33
SP - 3047
EP - 3054
JO - Journal of Clinical Oncology
JF - Journal of Clinical Oncology
SN - 0732-183X
IS - 27
ER -