Rare case of COVID-19 presenting as acute abdomen and sepsis

A. Alharthy; A. Balhamar; F. Faqihi; N. Nasim; A. F. Noor; S. A. Alqahtani; Z. A. Memish; D. Karakitsos

doi:10.1016/j.nmni.2020.100818

Rare case of COVID-19 presenting as acute abdomen and sepsis

A. Alharthy, A. Balhamar, F. Faqihi, N. Nasim, A. F. Noor, S. A. Alqahtani, Z. A. Memish, D. Karakitsos

School of Medicine

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Coronavirus disease 2019 (COVID-19) may present as acute abdomen, although the pathophysiology remains obscure. We report the case of a 45-year-old-man with severe COVID-19 pneumonia with associated pulmonary embolism who presented with acute abdomen. He underwent emergency laparotomy and resection of an ischaemic area of the jejunum. Postoperatively, he had septic shock, acute respiratory distress syndrome and acute kidney injury necessitating continuous renal replacement therapy. We administered antibiotics and therapeutic anticoagulation along with two sessions of haemoadsorption by CytoSorb filter, in conjunction with continuous renal replacement therapy. The patient survived. Bowel ischaemia due to thromboembolic disease should be promptly treated. Extracorporeal blood purification may be useful in managing sepsis in severe COVID-19.

Original language	English (US)
Article number	100818
Journal	New Microbes and New Infections
Volume	38
DOIs	https://doi.org/10.1016/j.nmni.2020.100818
State	Published - Nov 2020

Keywords

Acute abdomen
COVID-19
extracorporeal blood purification therapies
sepsis
thromboembolic disease

ASJC Scopus subject areas

Microbiology
Infectious Diseases

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10.1016/j.nmni.2020.100818

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title = "Rare case of COVID-19 presenting as acute abdomen and sepsis",

abstract = "Coronavirus disease 2019 (COVID-19) may present as acute abdomen, although the pathophysiology remains obscure. We report the case of a 45-year-old-man with severe COVID-19 pneumonia with associated pulmonary embolism who presented with acute abdomen. He underwent emergency laparotomy and resection of an ischaemic area of the jejunum. Postoperatively, he had septic shock, acute respiratory distress syndrome and acute kidney injury necessitating continuous renal replacement therapy. We administered antibiotics and therapeutic anticoagulation along with two sessions of haemoadsorption by CytoSorb filter, in conjunction with continuous renal replacement therapy. The patient survived. Bowel ischaemia due to thromboembolic disease should be promptly treated. Extracorporeal blood purification may be useful in managing sepsis in severe COVID-19.",

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AU - Alharthy, A.

AU - Balhamar, A.

AU - Faqihi, F.

AU - Nasim, N.

AU - Noor, A. F.

AU - Alqahtani, S. A.

AU - Memish, Z. A.

AU - Karakitsos, D.

PY - 2020/11

Y1 - 2020/11

N2 - Coronavirus disease 2019 (COVID-19) may present as acute abdomen, although the pathophysiology remains obscure. We report the case of a 45-year-old-man with severe COVID-19 pneumonia with associated pulmonary embolism who presented with acute abdomen. He underwent emergency laparotomy and resection of an ischaemic area of the jejunum. Postoperatively, he had septic shock, acute respiratory distress syndrome and acute kidney injury necessitating continuous renal replacement therapy. We administered antibiotics and therapeutic anticoagulation along with two sessions of haemoadsorption by CytoSorb filter, in conjunction with continuous renal replacement therapy. The patient survived. Bowel ischaemia due to thromboembolic disease should be promptly treated. Extracorporeal blood purification may be useful in managing sepsis in severe COVID-19.

AB - Coronavirus disease 2019 (COVID-19) may present as acute abdomen, although the pathophysiology remains obscure. We report the case of a 45-year-old-man with severe COVID-19 pneumonia with associated pulmonary embolism who presented with acute abdomen. He underwent emergency laparotomy and resection of an ischaemic area of the jejunum. Postoperatively, he had septic shock, acute respiratory distress syndrome and acute kidney injury necessitating continuous renal replacement therapy. We administered antibiotics and therapeutic anticoagulation along with two sessions of haemoadsorption by CytoSorb filter, in conjunction with continuous renal replacement therapy. The patient survived. Bowel ischaemia due to thromboembolic disease should be promptly treated. Extracorporeal blood purification may be useful in managing sepsis in severe COVID-19.

KW - Acute abdomen

KW - COVID-19

KW - extracorporeal blood purification therapies

KW - sepsis

KW - thromboembolic disease

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Rare case of COVID-19 presenting as acute abdomen and sepsis

Abstract

Keywords

ASJC Scopus subject areas

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