Rapidly progressive cutaneous Rhizopus microsporus infection presenting as Fournier's gangrene in a patient with acute myelogenous leukemia

Christine Durand, C. D. Alonso, A. P. Subhawong, N. P. Kwiatkowski, Margaret Showel, Karen C Carroll, Kieren Marr

Research output: Contribution to journalArticle

Abstract

Members of the genus Rhizopus within the class Zygomycetes can cause devastating opportunistic infections. Cutaneous disease arising from direct inoculation of fungal spores has the potential to disseminate widely. Here, we describe a dramatic case of cutaneous Rhizopus infection involving the penis in a patient with acute myelogenous leukemia. Despite aggressive surgical debridement, systemic antifungal therapy, and donor lymphocyte infusion, the infection was ultimately fatal. This case illustrates the unique diagnostic and therapeutic challenges in the clinical management of cutaneous Rhizopus infection.

Original languageEnglish (US)
Pages (from-to)392-396
Number of pages5
JournalTransplant Infectious Disease
Volume13
Issue number4
DOIs
Publication statusPublished - Aug 2011

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Keywords

  • Fournier's gangrene
  • Mucormycosis
  • Penile infection
  • Rhizopus
  • Zygomycetes
  • Zygomycosis

ASJC Scopus subject areas

  • Transplantation
  • Infectious Diseases

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