TY - JOUR
T1 - RAPID
T2 - Resource of Asian Primary Immunodeficiency Diseases
AU - Keerthikumar, Shivakumar
AU - Raju, Rajesh
AU - Kandasamy, Kumaran
AU - Hijikata, Atsushi
AU - Ramabadran, Subhashri
AU - Balakrishnan, Lavanya
AU - Ahmed, Mukhtar
AU - Rani, Sandhya
AU - Selvan, Lakshmi Dhevi N
AU - Somanathan, Devi S.
AU - Ray, Somak
AU - Bhattacharjee, Mitali
AU - Gollapudi, Sashikanth
AU - Ramachandra, Y. L.
AU - Bhadra, Sahely
AU - Bhattacharyya, Chiranjib
AU - Imai, Kohsuke
AU - Nonoyama, Shigeaki
AU - Kanegane, Hirokazu
AU - Miyawaki, Toshio
AU - Pandey, Akhilesh
AU - Ohara, Osamu
AU - Mohan, Sujatha
PY - 2009
Y1 - 2009
N2 - Availability of a freely accessible, dynamic and integrated database for primary immunodeficiency diseases (PID) is important both for researchers as well as clinicians. To build a PID informational platform and also as a part of action to initiate a network of PID research in Asia, we have constructed a web-based compendium of molecular alterations in PID, named Resource of Asian Primary Immunodeficiency Diseases (RAPID), which is available as a worldwide web resource at http://rapid.rcai.riken.jp/. It hosts information on sequence variations and expression at the mRNA and protein levels of all genes reported to be involved in PID patients. The main objective of this database is to provide detailed information pertaining to genes and proteins involved in primary immunodeficiency diseases along with other relevant information about protein-protein interactions, mouse studies and microarray gene-expression profiles in various organs and cells of the immune system. RAPID also hosts a tool, mutation viewer, to predict deleterious and novel mutations and also to obtain mutation-based 3D structures for PID genes. Thus, information contained in this database should help physicians and other biomedical investigators to further investigate the role of these molecules in PID.
AB - Availability of a freely accessible, dynamic and integrated database for primary immunodeficiency diseases (PID) is important both for researchers as well as clinicians. To build a PID informational platform and also as a part of action to initiate a network of PID research in Asia, we have constructed a web-based compendium of molecular alterations in PID, named Resource of Asian Primary Immunodeficiency Diseases (RAPID), which is available as a worldwide web resource at http://rapid.rcai.riken.jp/. It hosts information on sequence variations and expression at the mRNA and protein levels of all genes reported to be involved in PID patients. The main objective of this database is to provide detailed information pertaining to genes and proteins involved in primary immunodeficiency diseases along with other relevant information about protein-protein interactions, mouse studies and microarray gene-expression profiles in various organs and cells of the immune system. RAPID also hosts a tool, mutation viewer, to predict deleterious and novel mutations and also to obtain mutation-based 3D structures for PID genes. Thus, information contained in this database should help physicians and other biomedical investigators to further investigate the role of these molecules in PID.
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U2 - 10.1093/nar/gkn682
DO - 10.1093/nar/gkn682
M3 - Article
C2 - 18842635
AN - SCOPUS:58149177158
SN - 0305-1048
VL - 37
JO - Nucleic Acids Research
JF - Nucleic Acids Research
IS - SUPPL. 1
ER -