Rapid pulses of luteinizing hormone during the ovarian cycle

A. P. Murdoch, W. Dunlop, M. C. White, P. Kendall-Taylor, P. J. Diggle

Research output: Contribution to journalArticle

Abstract

Luteinizing hormone has been shown to be secreted in a complex pattern of low-amplitude, high-frequency pulses superimposed on high-amplitude, low-frequency pulses. To test the hypothesis that the rapid, small pulses vary during the ovarian cycle, 16 normal women were studied on two occasions each, in the early and late follicular phases of one cycle or the luteal and following early follicular phase. Blood samples were taken every 1 min for l h. Statistical methods of time series analysis were applied to the data. There were significant amplitude differences between subjects at all stages of the cycle. We found no evidence to support the hypothesis that the frequency of the small rapid pulses varied during folliculogenesis. The results for the luteal phase, while less uniform, showed no consistent change. It is suggested that the rapid pulses may be related to function of the hypothalamic-pituitary axis rather than direct ovarian control.

Original languageEnglish (US)
Pages (from-to)329-333
Number of pages5
JournalBritish Journal of Obstetrics and Gynaecology
Volume97
Issue number4
StatePublished - Apr 1990
Externally publishedYes

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Follicular Phase
Menstrual Cycle
Luteinizing Hormone
Luteal Phase
Corpus Luteum

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Murdoch, A. P., Dunlop, W., White, M. C., Kendall-Taylor, P., & Diggle, P. J. (1990). Rapid pulses of luteinizing hormone during the ovarian cycle. British Journal of Obstetrics and Gynaecology, 97(4), 329-333.

Rapid pulses of luteinizing hormone during the ovarian cycle. / Murdoch, A. P.; Dunlop, W.; White, M. C.; Kendall-Taylor, P.; Diggle, P. J.

In: British Journal of Obstetrics and Gynaecology, Vol. 97, No. 4, 04.1990, p. 329-333.

Research output: Contribution to journalArticle

Murdoch, AP, Dunlop, W, White, MC, Kendall-Taylor, P & Diggle, PJ 1990, 'Rapid pulses of luteinizing hormone during the ovarian cycle', British Journal of Obstetrics and Gynaecology, vol. 97, no. 4, pp. 329-333.
Murdoch AP, Dunlop W, White MC, Kendall-Taylor P, Diggle PJ. Rapid pulses of luteinizing hormone during the ovarian cycle. British Journal of Obstetrics and Gynaecology. 1990 Apr;97(4):329-333.
Murdoch, A. P. ; Dunlop, W. ; White, M. C. ; Kendall-Taylor, P. ; Diggle, P. J. / Rapid pulses of luteinizing hormone during the ovarian cycle. In: British Journal of Obstetrics and Gynaecology. 1990 ; Vol. 97, No. 4. pp. 329-333.
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