Abstract
Changes in the diffusion constant of water during reversible brain ischemia and cardiac arrest were monitored with a 10‐s time resolution. Results (five cats, three rats) indicate that these changes are reversible and that the bulk of the changes are not caused by temperature or motion related to brain pulsations and blood flow. The rapid time course of the changes corresponds to the known time course for changes in energy state, signal transduction, and ionic homeostasis.
Original language | English (US) |
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Pages (from-to) | 454-460 |
Number of pages | 7 |
Journal | Magnetic resonance in medicine |
Volume | 31 |
Issue number | 4 |
DOIs | |
State | Published - Apr 1994 |
Keywords
- NMR spectroscopy
- cerebral blood flow
- diffusion
- ischemia‐reperfusion
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging