Rapid monitoring of changes in water diffusion coefficients during reversible ischemia in cat and rat brain

D. Davis; J. Ulatowski; S. Eleff; M. Izuta; S. Mori; D. Shungu; P. C.M. van Zijl

doi:10.1002/mrm.1910310416

Rapid monitoring of changes in water diffusion coefficients during reversible ischemia in cat and rat brain

D. Davis, J. Ulatowski, S. Eleff, M. Izuta, S. Mori, D. Shungu, P. C.M. van Zijl

School of Medicine

Research output: Contribution to journal › Article › peer-review

143 Scopus citations

Abstract

Changes in the diffusion constant of water during reversible brain ischemia and cardiac arrest were monitored with a 10‐s time resolution. Results (five cats, three rats) indicate that these changes are reversible and that the bulk of the changes are not caused by temperature or motion related to brain pulsations and blood flow. The rapid time course of the changes corresponds to the known time course for changes in energy state, signal transduction, and ionic homeostasis.

Original language	English (US)
Pages (from-to)	454-460
Number of pages	7
Journal	Magnetic resonance in medicine
Volume	31
Issue number	4
DOIs	https://doi.org/10.1002/mrm.1910310416
State	Published - Apr 1994

Keywords

NMR spectroscopy
cerebral blood flow
diffusion
ischemia‐reperfusion

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1002/mrm.1910310416

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abstract = "Changes in the diffusion constant of water during reversible brain ischemia and cardiac arrest were monitored with a 10‐s time resolution. Results (five cats, three rats) indicate that these changes are reversible and that the bulk of the changes are not caused by temperature or motion related to brain pulsations and blood flow. The rapid time course of the changes corresponds to the known time course for changes in energy state, signal transduction, and ionic homeostasis.",

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AU - Mori, S.

AU - Shungu, D.

AU - van Zijl, P. C.M.

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AB - Changes in the diffusion constant of water during reversible brain ischemia and cardiac arrest were monitored with a 10‐s time resolution. Results (five cats, three rats) indicate that these changes are reversible and that the bulk of the changes are not caused by temperature or motion related to brain pulsations and blood flow. The rapid time course of the changes corresponds to the known time course for changes in energy state, signal transduction, and ionic homeostasis.

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Rapid monitoring of changes in water diffusion coefficients during reversible ischemia in cat and rat brain

Abstract

Keywords

ASJC Scopus subject areas

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