Rapid monitoring of changes in water diffusion coefficients during reversible ischemia in cat and rat brain

D. Davis, John A Ulatowski, S. Eleff, M. Izuta, Susumu Mori, D. Shungu, Peter C Van Zijl

Research output: Contribution to journalArticle


Changes in the diffusion constant of water during reversible brain ischemia and cardiac arrest were monitored with a 10-s time resolution. Results (five cats, three rats) indicate that these changes are reversible and that the bulk of the changes are not caused by temperature or motion related to brain pulsations and blood flow. The rapid time course of the changes corresponds to the known time course for changes in energy state, signal transduction, and ionic homeostasis.

Original languageEnglish (US)
Pages (from-to)454-460
Number of pages7
JournalMagnetic Resonance in Medicine
Issue number4
Publication statusPublished - 1994


ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

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