Rapid detection of malaria parasites

A. Feldman; J. Lin; S. Murphy; P. Demirev; D. Sullivan; P. Scholl; N. Kumar

Rapid detection of malaria parasites

A. Feldman, J. Lin, S. Murphy, P. Demirev, D. Sullivan, P. Scholl, N. Kumar

Research output: Contribution to journal › Article › peer-review

Abstract

APL and JHU Bloomberg School of Public Health researchers have demonstrated that laser desorption mass spectrometry (LDMS) was a sensitive method for detecting malaria parasites in the blood. The method is based on the detection of heme in hemozoin (Hz), the crystalline substance accumulated within malaria parasites during their intraerythrocytic growth stage. The LDMS test was performed without consumables other than a lancet and a container from blood collection. Blood was diluted in water, deposited onto a metal slide, sir dried, and inserted into the mass spectrometer for analysis. Hz heme was identified from the pattern of heme-molecular-structure-specific peaks.

Original language	English (US)
Pages (from-to)	232-233
Number of pages	2
Journal	Johns Hopkins APL Technical Digest (Applied Physics Laboratory)
Volume	28
Issue number	3
State	Published - Mar 16 2010

ASJC Scopus subject areas

Engineering(all)
Physics and Astronomy(all)

Cite this

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abstract = "APL and JHU Bloomberg School of Public Health researchers have demonstrated that laser desorption mass spectrometry (LDMS) was a sensitive method for detecting malaria parasites in the blood. The method is based on the detection of heme in hemozoin (Hz), the crystalline substance accumulated within malaria parasites during their intraerythrocytic growth stage. The LDMS test was performed without consumables other than a lancet and a container from blood collection. Blood was diluted in water, deposited onto a metal slide, sir dried, and inserted into the mass spectrometer for analysis. Hz heme was identified from the pattern of heme-molecular-structure-specific peaks.",

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T1 - Rapid detection of malaria parasites

AU - Feldman, A.

AU - Lin, J.

AU - Murphy, S.

AU - Demirev, P.

AU - Sullivan, D.

AU - Scholl, P.

AU - Kumar, N.

PY - 2010/3/16

Y1 - 2010/3/16

N2 - APL and JHU Bloomberg School of Public Health researchers have demonstrated that laser desorption mass spectrometry (LDMS) was a sensitive method for detecting malaria parasites in the blood. The method is based on the detection of heme in hemozoin (Hz), the crystalline substance accumulated within malaria parasites during their intraerythrocytic growth stage. The LDMS test was performed without consumables other than a lancet and a container from blood collection. Blood was diluted in water, deposited onto a metal slide, sir dried, and inserted into the mass spectrometer for analysis. Hz heme was identified from the pattern of heme-molecular-structure-specific peaks.

AB - APL and JHU Bloomberg School of Public Health researchers have demonstrated that laser desorption mass spectrometry (LDMS) was a sensitive method for detecting malaria parasites in the blood. The method is based on the detection of heme in hemozoin (Hz), the crystalline substance accumulated within malaria parasites during their intraerythrocytic growth stage. The LDMS test was performed without consumables other than a lancet and a container from blood collection. Blood was diluted in water, deposited onto a metal slide, sir dried, and inserted into the mass spectrometer for analysis. Hz heme was identified from the pattern of heme-molecular-structure-specific peaks.

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M3 - Article

AN - SCOPUS:77949287871

VL - 28

SP - 232

EP - 233

JO - Johns Hopkins APL Technical Digest (Applied Physics Laboratory)

JF - Johns Hopkins APL Technical Digest (Applied Physics Laboratory)

SN - 0270-5214

IS - 3

ER -

Rapid detection of malaria parasites

Abstract

ASJC Scopus subject areas

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