Abstract
APL and JHU Bloomberg School of Public Health researchers have demonstrated that laser desorption mass spectrometry (LDMS) was a sensitive method for detecting malaria parasites in the blood. The method is based on the detection of heme in hemozoin (Hz), the crystalline substance accumulated within malaria parasites during their intraerythrocytic growth stage. The LDMS test was performed without consumables other than a lancet and a container from blood collection. Blood was diluted in water, deposited onto a metal slide, sir dried, and inserted into the mass spectrometer for analysis. Hz heme was identified from the pattern of heme-molecular-structure-specific peaks.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 232-233 |
| Number of pages | 2 |
| Journal | Johns Hopkins APL Technical Digest (Applied Physics Laboratory) |
| Volume | 28 |
| Issue number | 3 |
| State | Published - 2010 |
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ASJC Scopus subject areas
- Engineering(all)
- Physics and Astronomy(all)
Cite this
Rapid detection of malaria parasites. / Feldman, A.; Lin, J.; Murphy, S.; Demirev, P.; Sullivan, David J; Scholl, P.; Kumar, N.
In: Johns Hopkins APL Technical Digest (Applied Physics Laboratory), Vol. 28, No. 3, 2010, p. 232-233.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Rapid detection of malaria parasites
AU - Feldman, A.
AU - Lin, J.
AU - Murphy, S.
AU - Demirev, P.
AU - Sullivan, David J
AU - Scholl, P.
AU - Kumar, N.
PY - 2010
Y1 - 2010
N2 - APL and JHU Bloomberg School of Public Health researchers have demonstrated that laser desorption mass spectrometry (LDMS) was a sensitive method for detecting malaria parasites in the blood. The method is based on the detection of heme in hemozoin (Hz), the crystalline substance accumulated within malaria parasites during their intraerythrocytic growth stage. The LDMS test was performed without consumables other than a lancet and a container from blood collection. Blood was diluted in water, deposited onto a metal slide, sir dried, and inserted into the mass spectrometer for analysis. Hz heme was identified from the pattern of heme-molecular-structure-specific peaks.
AB - APL and JHU Bloomberg School of Public Health researchers have demonstrated that laser desorption mass spectrometry (LDMS) was a sensitive method for detecting malaria parasites in the blood. The method is based on the detection of heme in hemozoin (Hz), the crystalline substance accumulated within malaria parasites during their intraerythrocytic growth stage. The LDMS test was performed without consumables other than a lancet and a container from blood collection. Blood was diluted in water, deposited onto a metal slide, sir dried, and inserted into the mass spectrometer for analysis. Hz heme was identified from the pattern of heme-molecular-structure-specific peaks.
UR - http://www.scopus.com/inward/record.url?scp=77949287871&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77949287871&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:77949287871
VL - 28
SP - 232
EP - 233
JO - Johns Hopkins APL Technical Digest (Applied Physics Laboratory)
JF - Johns Hopkins APL Technical Digest (Applied Physics Laboratory)
SN - 0270-5214
IS - 3
ER -