Randomized trial of achieving healthy lifestyles in psychiatric rehabilitation: The ACHIEVE trial

Sarah S. Casagrande; Gerald J. Jerome; Arlene T. Dalcin; Faith B. Dickerson; Cheryl A. Anderson; Lawrence J. Appel; Jeanne Charleston; Rosa M. Crum; Deborah R. Young; Eliseo Guallar; Kevin D. Frick; Richard W. Goldberg; Meghan Oefinger; Joseph Finkelstein; Joseph V. Gennusa; Oladapo Fred-Omojole; Leslie M. Campbell; Nae Yuh Wang; Gail L. Daumit

doi:10.1186/1471-244X-10-108

Randomized trial of achieving healthy lifestyles in psychiatric rehabilitation: The ACHIEVE trial

Sarah S. Casagrande, Gerald J. Jerome, Arlene T. Dalcin, Faith B. Dickerson, Cheryl A. Anderson, Lawrence J. Appel, Jeanne Charleston, Rosa M. Crum, Deborah R. Young, Eliseo Guallar, Kevin D. Frick, Richard W. Goldberg, Meghan Oefinger, Joseph Finkelstein, Joseph V. Gennusa, Oladapo Fred-Omojole, Leslie M. Campbell, Nae Yuh Wang, Gail L. Daumit

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

Background: Overweight and obesity are highly prevalent among persons with serious mental illness. These conditions likely contribute to premature cardiovascular disease and a 20 to 30 percent shortened life expectancy in this vulnerable population. Persons with serious mental illness need effective, appropriately tailored behavioral interventions to achieve and maintain weight loss. Psychiatric rehabilitation day programs provide logical intervention settings because mental health consumers often attend regularly and exercise can take place on-site. This paper describes the Randomized Trial of Achieving Healthy Lifestyles in Psychiatric Rehabilitation (ACHIEVE). The goal of the study is to determine the effectiveness of a behavioral weight loss intervention among persons with serious mental illness that attend psychiatric rehabilitation programs. Participants randomized to the intervention arm of the study are hypothesized to have greater weight loss than the control group.Methods/Design: A targeted 320 men and women with serious mental illness and overweight or obesity (body mass index ≥ 25.0 kg/m²) will be recruited from 10 psychiatric rehabilitation programs across Maryland. The core design is a randomized, two-arm, parallel, multi-site clinical trial to compare the effectiveness of an 18-month behavioral weight loss intervention to usual care. Active intervention participants receive weight management sessions and physical activity classes on-site led by study interventionists. The intervention incorporates cognitive adaptations for persons with serious mental illness attending psychiatric rehabilitation programs. The initial intensive intervention period is six months, followed by a twelve-month maintenance period in which trained rehabilitation program staff assume responsibility for delivering parts of the intervention. Primary outcomes are weight loss at six and 18 months.Discussion: Evidence-based approaches to the high burden of obesity and cardiovascular disease risk in person with serious mental illness are urgently needed. The ACHIEVE Trial is tailored to persons with serious mental illness in community settings. This multi-site randomized clinical trial will provide a rigorous evaluation of a practical behavioral intervention designed to accomplish and sustain weight loss in persons with serious mental illness.

Original language	English (US)
Article number	108
Journal	BMC psychiatry
Volume	10
DOIs	https://doi.org/10.1186/1471-244X-10-108
State	Published - Dec 13 2010

ASJC Scopus subject areas

Psychiatry and Mental health

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10.1186/1471-244X-10-108

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Casagrande, S. S., Jerome, G. J., Dalcin, A. T., Dickerson, F. B., Anderson, C. A., Appel, L. J., Charleston, J., Crum, R. M., Young, D. R., Guallar, E., Frick, K. D., Goldberg, R. W., Oefinger, M., Finkelstein, J., Gennusa, J. V., Fred-Omojole, O., Campbell, L. M., Wang, N. Y., & Daumit, G. L. (2010). Randomized trial of achieving healthy lifestyles in psychiatric rehabilitation: The ACHIEVE trial. BMC psychiatry, 10, Article 108. https://doi.org/10.1186/1471-244X-10-108

Casagrande, SS, Jerome, GJ, Dalcin, AT, Dickerson, FB, Anderson, CA, Appel, LJ , Charleston, J , Crum, RM, Young, DR, Guallar, E , Frick, KD, Goldberg, RW, Oefinger, M, Finkelstein, J, Gennusa, JV, Fred-Omojole, O, Campbell, LM, Wang, NY & Daumit, GL 2010, 'Randomized trial of achieving healthy lifestyles in psychiatric rehabilitation: The ACHIEVE trial', BMC psychiatry, vol. 10, 108. https://doi.org/10.1186/1471-244X-10-108

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title = "Randomized trial of achieving healthy lifestyles in psychiatric rehabilitation: The ACHIEVE trial",

abstract = "Background: Overweight and obesity are highly prevalent among persons with serious mental illness. These conditions likely contribute to premature cardiovascular disease and a 20 to 30 percent shortened life expectancy in this vulnerable population. Persons with serious mental illness need effective, appropriately tailored behavioral interventions to achieve and maintain weight loss. Psychiatric rehabilitation day programs provide logical intervention settings because mental health consumers often attend regularly and exercise can take place on-site. This paper describes the Randomized Trial of Achieving Healthy Lifestyles in Psychiatric Rehabilitation (ACHIEVE). The goal of the study is to determine the effectiveness of a behavioral weight loss intervention among persons with serious mental illness that attend psychiatric rehabilitation programs. Participants randomized to the intervention arm of the study are hypothesized to have greater weight loss than the control group.Methods/Design: A targeted 320 men and women with serious mental illness and overweight or obesity (body mass index ≥ 25.0 kg/m2) will be recruited from 10 psychiatric rehabilitation programs across Maryland. The core design is a randomized, two-arm, parallel, multi-site clinical trial to compare the effectiveness of an 18-month behavioral weight loss intervention to usual care. Active intervention participants receive weight management sessions and physical activity classes on-site led by study interventionists. The intervention incorporates cognitive adaptations for persons with serious mental illness attending psychiatric rehabilitation programs. The initial intensive intervention period is six months, followed by a twelve-month maintenance period in which trained rehabilitation program staff assume responsibility for delivering parts of the intervention. Primary outcomes are weight loss at six and 18 months.Discussion: Evidence-based approaches to the high burden of obesity and cardiovascular disease risk in person with serious mental illness are urgently needed. The ACHIEVE Trial is tailored to persons with serious mental illness in community settings. This multi-site randomized clinical trial will provide a rigorous evaluation of a practical behavioral intervention designed to accomplish and sustain weight loss in persons with serious mental illness.",

author = "Casagrande, {Sarah S.} and Jerome, {Gerald J.} and Dalcin, {Arlene T.} and Dickerson, {Faith B.} and Anderson, {Cheryl A.} and Appel, {Lawrence J.} and Jeanne Charleston and Crum, {Rosa M.} and Young, {Deborah R.} and Eliseo Guallar and Frick, {Kevin D.} and Goldberg, {Richard W.} and Meghan Oefinger and Joseph Finkelstein and Gennusa, {Joseph V.} and Oladapo Fred-Omojole and Campbell, {Leslie M.} and Wang, {Nae Yuh} and Daumit, {Gail L.}",

note = "Funding Information: Funding for this study is provided by the National Institute of Mental Health, Grant R01MH080964",

year = "2010",

month = dec,

day = "13",

doi = "10.1186/1471-244X-10-108",

language = "English (US)",

volume = "10",

journal = "BMC psychiatry",

issn = "1471-244X",

publisher = "BioMed Central",

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TY - JOUR

T1 - Randomized trial of achieving healthy lifestyles in psychiatric rehabilitation

T2 - The ACHIEVE trial

AU - Casagrande, Sarah S.

AU - Jerome, Gerald J.

AU - Dalcin, Arlene T.

AU - Dickerson, Faith B.

AU - Anderson, Cheryl A.

AU - Appel, Lawrence J.

AU - Charleston, Jeanne

AU - Crum, Rosa M.

AU - Young, Deborah R.

AU - Guallar, Eliseo

AU - Frick, Kevin D.

AU - Goldberg, Richard W.

AU - Oefinger, Meghan

AU - Finkelstein, Joseph

AU - Gennusa, Joseph V.

AU - Fred-Omojole, Oladapo

AU - Campbell, Leslie M.

AU - Wang, Nae Yuh

AU - Daumit, Gail L.

N1 - Funding Information: Funding for this study is provided by the National Institute of Mental Health, Grant R01MH080964

PY - 2010/12/13

Y1 - 2010/12/13

N2 - Background: Overweight and obesity are highly prevalent among persons with serious mental illness. These conditions likely contribute to premature cardiovascular disease and a 20 to 30 percent shortened life expectancy in this vulnerable population. Persons with serious mental illness need effective, appropriately tailored behavioral interventions to achieve and maintain weight loss. Psychiatric rehabilitation day programs provide logical intervention settings because mental health consumers often attend regularly and exercise can take place on-site. This paper describes the Randomized Trial of Achieving Healthy Lifestyles in Psychiatric Rehabilitation (ACHIEVE). The goal of the study is to determine the effectiveness of a behavioral weight loss intervention among persons with serious mental illness that attend psychiatric rehabilitation programs. Participants randomized to the intervention arm of the study are hypothesized to have greater weight loss than the control group.Methods/Design: A targeted 320 men and women with serious mental illness and overweight or obesity (body mass index ≥ 25.0 kg/m2) will be recruited from 10 psychiatric rehabilitation programs across Maryland. The core design is a randomized, two-arm, parallel, multi-site clinical trial to compare the effectiveness of an 18-month behavioral weight loss intervention to usual care. Active intervention participants receive weight management sessions and physical activity classes on-site led by study interventionists. The intervention incorporates cognitive adaptations for persons with serious mental illness attending psychiatric rehabilitation programs. The initial intensive intervention period is six months, followed by a twelve-month maintenance period in which trained rehabilitation program staff assume responsibility for delivering parts of the intervention. Primary outcomes are weight loss at six and 18 months.Discussion: Evidence-based approaches to the high burden of obesity and cardiovascular disease risk in person with serious mental illness are urgently needed. The ACHIEVE Trial is tailored to persons with serious mental illness in community settings. This multi-site randomized clinical trial will provide a rigorous evaluation of a practical behavioral intervention designed to accomplish and sustain weight loss in persons with serious mental illness.

AB - Background: Overweight and obesity are highly prevalent among persons with serious mental illness. These conditions likely contribute to premature cardiovascular disease and a 20 to 30 percent shortened life expectancy in this vulnerable population. Persons with serious mental illness need effective, appropriately tailored behavioral interventions to achieve and maintain weight loss. Psychiatric rehabilitation day programs provide logical intervention settings because mental health consumers often attend regularly and exercise can take place on-site. This paper describes the Randomized Trial of Achieving Healthy Lifestyles in Psychiatric Rehabilitation (ACHIEVE). The goal of the study is to determine the effectiveness of a behavioral weight loss intervention among persons with serious mental illness that attend psychiatric rehabilitation programs. Participants randomized to the intervention arm of the study are hypothesized to have greater weight loss than the control group.Methods/Design: A targeted 320 men and women with serious mental illness and overweight or obesity (body mass index ≥ 25.0 kg/m2) will be recruited from 10 psychiatric rehabilitation programs across Maryland. The core design is a randomized, two-arm, parallel, multi-site clinical trial to compare the effectiveness of an 18-month behavioral weight loss intervention to usual care. Active intervention participants receive weight management sessions and physical activity classes on-site led by study interventionists. The intervention incorporates cognitive adaptations for persons with serious mental illness attending psychiatric rehabilitation programs. The initial intensive intervention period is six months, followed by a twelve-month maintenance period in which trained rehabilitation program staff assume responsibility for delivering parts of the intervention. Primary outcomes are weight loss at six and 18 months.Discussion: Evidence-based approaches to the high burden of obesity and cardiovascular disease risk in person with serious mental illness are urgently needed. The ACHIEVE Trial is tailored to persons with serious mental illness in community settings. This multi-site randomized clinical trial will provide a rigorous evaluation of a practical behavioral intervention designed to accomplish and sustain weight loss in persons with serious mental illness.

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Randomized trial of achieving healthy lifestyles in psychiatric rehabilitation: The ACHIEVE trial

Abstract

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