Randomized, controlled trial efficacy of pneumococcal conjugate vaccine against otitis media among navajo and white mountain apache infants

Research output: Contribution to journalArticlepeer-review

Abstract

We report the phase III trial efficacy of 7-valent pneumococcal conjugate vaccine against clinical and culture proven otitis media (OM) among Navajo and White Mountain Apache infants. Efficacy was -0.4% (95% CI: -19.4 to 15.6) for clinically-diagnosed OM, 5.1% (95% CI: -51.5 to 40.6) for severe OM, and 64% (95% CI: -34% to 90%) for vaccine serotype pneumococcal OM suggesting that this vaccine is efficacious for pneumococcal OM in this high risk population.

Original languageEnglish (US)
Pages (from-to)71-73
Number of pages3
JournalPediatric Infectious Disease Journal
Volume27
Issue number1
DOIs
StatePublished - Jan 2008

Keywords

  • American Indian
  • Otitis media
  • Pneumococcal conjugate vaccine
  • Pneumococcus
  • Randomized clinical trial
  • Streptococcus pneumonia

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Microbiology (medical)
  • Infectious Diseases

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