Randomized clinical trials: Issues for researchers

Marilyn S. Fetter, Suzanne L. Feetham, Karen D’Apouto, Betti Ann Ciiaze, Arlene Fink, Barbara B. Frink, Margaret Houcart, Cindy Rusiiton

Research output: Contribution to journalArticlepeer-review

Abstract

The clinical trial is a randomized prospective study of human subjects in which the effectiveness of an intervention is compared against a control Such a trial is considered to be a critical test of an innovative therapy Trials require careful design and planning to be scientifically valid and clinically pertinent In this review the clinical trial and its role in research are defined, and major ethical, methodological, and feasibility issues associated with trial design and organization are described.

Original languageEnglish (US)
Pages (from-to)117-120
Number of pages4
JournalNursing research
Volume38
Issue number2
StatePublished - 1989

ASJC Scopus subject areas

  • Nursing(all)

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