Abstract
Oncolytic viruses exploit molecular differences between normal and cancer cells to selectively kill the latter. Results of a synthetic lethal screen described in this issue of Cancer Cell demonstrate that components of the unfolded protein response (UPR) limit virus-induced tumor cell killing and identify a strategy to utilize this knowledge.
Original language | English (US) |
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Pages (from-to) | 416-418 |
Number of pages | 3 |
Journal | Cancer cell |
Volume | 20 |
Issue number | 4 |
DOIs | |
State | Published - Oct 18 2011 |
Externally published | Yes |
ASJC Scopus subject areas
- Oncology
- Cell Biology
- Cancer Research