Radiosynthesis of [11C]‐N‐methylacyclovir

Alan A. Wilson, Peter S. Conti, Robert F. Dannals, Hayden T. Ravert, Henry N. Wagner

Research output: Contribution to journalArticlepeer-review

Abstract

A selective and potent analogue of the anti‐herpes agent acyclovir has been labelled with 11C in good yield and at high specific activities. 1‐[11C]‐Methyl‐9‐(2‐hydroxyethoxy)methyl)guanine may be useful for detecting HSV encephalitis using positron emission tomography.

Original languageEnglish (US)
Pages (from-to)765-768
Number of pages4
JournalJournal of Labelled Compounds and Radiopharmaceuticals
Volume29
Issue number7
DOIs
StatePublished - Jul 1991

Keywords

  • HSV encephalitis
  • PET
  • acyclovir
  • carbon‐11

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Radiology Nuclear Medicine and imaging
  • Drug Discovery
  • Spectroscopy
  • Organic Chemistry

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