Radiosynthesis of an opiate receptor binding radiotracer: [11C]carfentanil

Robert F. Dannals, Hayden T. Ravert, J. James Frost, Alan A. Wilson, H. Donald Burns, Henry N. Wagner

Research output: Contribution to journalArticle

Abstract

Carfentanil, a potent opiate receptor agonist, was labeled with 11C for in vito studies using positron emission tomography. This synthesis was completed in approximately 30 min using iodomethane as the 11C precursor. The synthesis, purification, characterization, and determination of specific activity are presented and discussed.

Original languageEnglish (US)
Pages (from-to)303-306
Number of pages4
JournalThe International Journal Of Applied Radiation And Isotopes
Volume36
Issue number4
DOIs
StatePublished - 1985

ASJC Scopus subject areas

  • Nuclear Energy and Engineering
  • Radiology Nuclear Medicine and imaging
  • Radiation

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    Dannals, R. F., Ravert, H. T., James Frost, J., Wilson, A. A., Donald Burns, H., & Wagner, H. N. (1985). Radiosynthesis of an opiate receptor binding radiotracer: [11C]carfentanil. The International Journal Of Applied Radiation And Isotopes, 36(4), 303-306. https://doi.org/10.1016/0020-708X(85)90089-4