### Abstract

Photon point dose kernels and absorbed fractions were generated in water for the full photon emission spectrum of each radionuclide of interest in nuclear medicine, by simulating the transport of particles using Monte Carlo. The kernels were then fitted to a mathematical expression. Absorbed fractions for point sources were obtained by integrating the kernels over spheres. Photon dose kernels and absorbed fractions were generated for the following radionuclides: I-123, I-124, I-125, I-131, In-111, Cu-64, Cu-67, Ga-67, Ga- 68, Re-186, Re-188, Sm-153, Sn-117m, Tc-99m. The Monte Carlo simulation was verified by comparing the dose kernels to published monoenergetic photon kernels. Further validation was obtained by generating an I-125 brachytherapy seed kernel and comparing it with published data. Since Monte Carlo simulation was initialized by sampling from the complete photon spectra of these radionuclides, interpolation between monoenergetic kernels and absorbed fractions was not required. The absorbed-fraction due to uniform spherical distributions can be directly applied for use in internal dosimetry. In addition, the kernels can be used as input for three-dimensional internal dosimetry calculations.

Original language | English (US) |
---|---|

Pages (from-to) | 759-764 |

Number of pages | 6 |

Journal | Medical Physics |

Volume | 23 |

Issue number | 5 |

DOIs | |

State | Published - 1996 |

Externally published | Yes |

### Fingerprint

### Keywords

- absorbed fractions
- dose kernels
- internal dosimetry
- Monte Carlo
- radioimmunotherapy

### ASJC Scopus subject areas

- Biophysics

### Cite this

*Medical Physics*,

*23*(5), 759-764. https://doi.org/10.1118/1.597670

**Radionuclide photon dose kernels for internal emitter dosimetry.** / Furhang, Eli E.; Sgouros, George; Chui, Chen Shou.

Research output: Contribution to journal › Article

*Medical Physics*, vol. 23, no. 5, pp. 759-764. https://doi.org/10.1118/1.597670

}

TY - JOUR

T1 - Radionuclide photon dose kernels for internal emitter dosimetry

AU - Furhang, Eli E.

AU - Sgouros, George

AU - Chui, Chen Shou

PY - 1996

Y1 - 1996

N2 - Photon point dose kernels and absorbed fractions were generated in water for the full photon emission spectrum of each radionuclide of interest in nuclear medicine, by simulating the transport of particles using Monte Carlo. The kernels were then fitted to a mathematical expression. Absorbed fractions for point sources were obtained by integrating the kernels over spheres. Photon dose kernels and absorbed fractions were generated for the following radionuclides: I-123, I-124, I-125, I-131, In-111, Cu-64, Cu-67, Ga-67, Ga- 68, Re-186, Re-188, Sm-153, Sn-117m, Tc-99m. The Monte Carlo simulation was verified by comparing the dose kernels to published monoenergetic photon kernels. Further validation was obtained by generating an I-125 brachytherapy seed kernel and comparing it with published data. Since Monte Carlo simulation was initialized by sampling from the complete photon spectra of these radionuclides, interpolation between monoenergetic kernels and absorbed fractions was not required. The absorbed-fraction due to uniform spherical distributions can be directly applied for use in internal dosimetry. In addition, the kernels can be used as input for three-dimensional internal dosimetry calculations.

AB - Photon point dose kernels and absorbed fractions were generated in water for the full photon emission spectrum of each radionuclide of interest in nuclear medicine, by simulating the transport of particles using Monte Carlo. The kernels were then fitted to a mathematical expression. Absorbed fractions for point sources were obtained by integrating the kernels over spheres. Photon dose kernels and absorbed fractions were generated for the following radionuclides: I-123, I-124, I-125, I-131, In-111, Cu-64, Cu-67, Ga-67, Ga- 68, Re-186, Re-188, Sm-153, Sn-117m, Tc-99m. The Monte Carlo simulation was verified by comparing the dose kernels to published monoenergetic photon kernels. Further validation was obtained by generating an I-125 brachytherapy seed kernel and comparing it with published data. Since Monte Carlo simulation was initialized by sampling from the complete photon spectra of these radionuclides, interpolation between monoenergetic kernels and absorbed fractions was not required. The absorbed-fraction due to uniform spherical distributions can be directly applied for use in internal dosimetry. In addition, the kernels can be used as input for three-dimensional internal dosimetry calculations.

KW - absorbed fractions

KW - dose kernels

KW - internal dosimetry

KW - Monte Carlo

KW - radioimmunotherapy

UR - http://www.scopus.com/inward/record.url?scp=0029946917&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029946917&partnerID=8YFLogxK

U2 - 10.1118/1.597670

DO - 10.1118/1.597670

M3 - Article

C2 - 8724750

AN - SCOPUS:0029946917

VL - 23

SP - 759

EP - 764

JO - Medical Physics

JF - Medical Physics

SN - 0094-2405

IS - 5

ER -