Radiomics: a new application from established techniques

Vishwa Parekh, Michael Jacobs

Research output: Contribution to journalReview article

Abstract

The increasing use of biomarkers in cancer have led to the concept of personalized medicine for patients. Personalized medicine provides better diagnosis and treatment options available to clinicians. Radiological imaging techniques provide an opportunity to deliver unique data on different types of tissue. However, obtaining useful information from all radiological data is challenging in the era of ‘big data’. Recent advances in computational power and the use of genomics have generated a new area of research termed Radiomics. Radiomics is defined as the high throughput extraction of quantitative imaging features or texture (radiomics) from imaging to decode tissue pathology and creating a high dimensional data set for feature extraction. Radiomic features provide information about the gray-scale patterns, inter-pixel relationships. In addition, shape and spectral properties can be extracted within the same regions of interest on radiological images. Moreover, these features can be further used to develop computational models using advanced machine learning algorithms that may serve as a tool for personalized diagnosis and treatment guidance.

Original languageEnglish (US)
Pages (from-to)207-226
Number of pages20
JournalExpert Review of Precision Medicine and Drug Development
Volume1
Issue number2
DOIs
StatePublished - Mar 3 2016

Keywords

  • ADC map
  • Breast
  • cancer
  • diffusion-weighted imaging
  • DWI
  • genetics
  • informatics
  • machine learning
  • Magnetic Resonance Imaging
  • proton
  • Radiomics
  • texture
  • treatment response

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery
  • Molecular Medicine
  • Genetics

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