Radiologist detection of microcalcifications with and without computer-aided detection: A comparative study

Rachel F. Brem, Joelle M. Schoonjans

Research output: Contribution to journalArticle

Abstract

Aim: To compare the sensitivity and specificity of microcalcification detection by radiologists alone and assisted by a computer-aided detection (CAD) system. Materials and Methods: Films of 106 patients were masked, randomized, digitized and analysed by the CAD-system. Five readers interpreted the original mammograms and were blinded to demographics, medical history and earlier films. Forty-two mammograms with malignant microcalcifications, 40 with benign microcalcifications; and 24 normal mammograms were included. Results were recorded on a standardized image interpretation form. The mammograms with suspicious areas flagged by the CAD-system were displayed on mini-monitors and immediately re-reviewed. The interpretation was again recorded on a new copy of the standard form and classified according to six groups. Results: Forty-one out of 42 (98%) malignant microcalcifications and 32 of 40 (80%) benign microcalcifications were flagged by the CAD-system. There was an average of 1.2 markers per image. The sensitivity for malignant microcalcifications detection by mammographers without and with the CAD-system ranged from 81% to 98% and from 88% to 98%, respectively. The mean difference without and with CAD-system was 2.2% (range 0-7%). Conclusion: No statistically significant changes in sensitivity were found when experienced mammographers were assisted by the CAD-system, with no significant compromise in specificity.

Original languageEnglish (US)
Pages (from-to)150-154
Number of pages5
JournalClinical Radiology
Volume56
Issue number2
DOIs
StatePublished - Feb 2001

Fingerprint

Calcinosis
Radiologists
Demography
Sensitivity and Specificity

Keywords

  • CAD
  • Mammogram
  • Microcalcification

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging

Cite this

Radiologist detection of microcalcifications with and without computer-aided detection : A comparative study. / Brem, Rachel F.; Schoonjans, Joelle M.

In: Clinical Radiology, Vol. 56, No. 2, 02.2001, p. 150-154.

Research output: Contribution to journalArticle

Brem, Rachel F. ; Schoonjans, Joelle M. / Radiologist detection of microcalcifications with and without computer-aided detection : A comparative study. In: Clinical Radiology. 2001 ; Vol. 56, No. 2. pp. 150-154.
@article{b05b0219a27e4385ba05003a4adc360c,
title = "Radiologist detection of microcalcifications with and without computer-aided detection: A comparative study",
abstract = "Aim: To compare the sensitivity and specificity of microcalcification detection by radiologists alone and assisted by a computer-aided detection (CAD) system. Materials and Methods: Films of 106 patients were masked, randomized, digitized and analysed by the CAD-system. Five readers interpreted the original mammograms and were blinded to demographics, medical history and earlier films. Forty-two mammograms with malignant microcalcifications, 40 with benign microcalcifications; and 24 normal mammograms were included. Results were recorded on a standardized image interpretation form. The mammograms with suspicious areas flagged by the CAD-system were displayed on mini-monitors and immediately re-reviewed. The interpretation was again recorded on a new copy of the standard form and classified according to six groups. Results: Forty-one out of 42 (98{\%}) malignant microcalcifications and 32 of 40 (80{\%}) benign microcalcifications were flagged by the CAD-system. There was an average of 1.2 markers per image. The sensitivity for malignant microcalcifications detection by mammographers without and with the CAD-system ranged from 81{\%} to 98{\%} and from 88{\%} to 98{\%}, respectively. The mean difference without and with CAD-system was 2.2{\%} (range 0-7{\%}). Conclusion: No statistically significant changes in sensitivity were found when experienced mammographers were assisted by the CAD-system, with no significant compromise in specificity.",
keywords = "CAD, Mammogram, Microcalcification",
author = "Brem, {Rachel F.} and Schoonjans, {Joelle M.}",
year = "2001",
month = "2",
doi = "10.1053/crad.2000.0592",
language = "English (US)",
volume = "56",
pages = "150--154",
journal = "Clinical Radiology",
issn = "0009-9260",
publisher = "W.B. Saunders Ltd",
number = "2",

}

TY - JOUR

T1 - Radiologist detection of microcalcifications with and without computer-aided detection

T2 - A comparative study

AU - Brem, Rachel F.

AU - Schoonjans, Joelle M.

PY - 2001/2

Y1 - 2001/2

N2 - Aim: To compare the sensitivity and specificity of microcalcification detection by radiologists alone and assisted by a computer-aided detection (CAD) system. Materials and Methods: Films of 106 patients were masked, randomized, digitized and analysed by the CAD-system. Five readers interpreted the original mammograms and were blinded to demographics, medical history and earlier films. Forty-two mammograms with malignant microcalcifications, 40 with benign microcalcifications; and 24 normal mammograms were included. Results were recorded on a standardized image interpretation form. The mammograms with suspicious areas flagged by the CAD-system were displayed on mini-monitors and immediately re-reviewed. The interpretation was again recorded on a new copy of the standard form and classified according to six groups. Results: Forty-one out of 42 (98%) malignant microcalcifications and 32 of 40 (80%) benign microcalcifications were flagged by the CAD-system. There was an average of 1.2 markers per image. The sensitivity for malignant microcalcifications detection by mammographers without and with the CAD-system ranged from 81% to 98% and from 88% to 98%, respectively. The mean difference without and with CAD-system was 2.2% (range 0-7%). Conclusion: No statistically significant changes in sensitivity were found when experienced mammographers were assisted by the CAD-system, with no significant compromise in specificity.

AB - Aim: To compare the sensitivity and specificity of microcalcification detection by radiologists alone and assisted by a computer-aided detection (CAD) system. Materials and Methods: Films of 106 patients were masked, randomized, digitized and analysed by the CAD-system. Five readers interpreted the original mammograms and were blinded to demographics, medical history and earlier films. Forty-two mammograms with malignant microcalcifications, 40 with benign microcalcifications; and 24 normal mammograms were included. Results were recorded on a standardized image interpretation form. The mammograms with suspicious areas flagged by the CAD-system were displayed on mini-monitors and immediately re-reviewed. The interpretation was again recorded on a new copy of the standard form and classified according to six groups. Results: Forty-one out of 42 (98%) malignant microcalcifications and 32 of 40 (80%) benign microcalcifications were flagged by the CAD-system. There was an average of 1.2 markers per image. The sensitivity for malignant microcalcifications detection by mammographers without and with the CAD-system ranged from 81% to 98% and from 88% to 98%, respectively. The mean difference without and with CAD-system was 2.2% (range 0-7%). Conclusion: No statistically significant changes in sensitivity were found when experienced mammographers were assisted by the CAD-system, with no significant compromise in specificity.

KW - CAD

KW - Mammogram

KW - Microcalcification

UR - http://www.scopus.com/inward/record.url?scp=0035248053&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035248053&partnerID=8YFLogxK

U2 - 10.1053/crad.2000.0592

DO - 10.1053/crad.2000.0592

M3 - Article

C2 - 11222075

AN - SCOPUS:0035248053

VL - 56

SP - 150

EP - 154

JO - Clinical Radiology

JF - Clinical Radiology

SN - 0009-9260

IS - 2

ER -