TY - JOUR
T1 - Radiofrequency ablation versus cryoablation in the treatment of paroxysmal atrial fibrillation
T2 - A meta-Analysis
AU - Hachem, Ali H.
AU - Marine, Joseph E.
AU - Tahboub, Housam A.
AU - Kamdar, Sana
AU - Kanjwal, Shaffi
AU - Soni, Ronak
AU - Kanjwal, Khalil
N1 - Publisher Copyright:
© 2018 Ali H. Hachem et al.
PY - 2018
Y1 - 2018
N2 - Background. Pulmonary vein isolation is commonly performed using radiofrequency energy with cryoablation gaining acceptance. We performed a meta-Analysis of randomized controlled trials which compared radiofrequency versus cryoablation for patients with atrial fibrillation. Methods. A systematic search strategy identified both published and unpublished articles from inception to November 10, 2016, in multiple databases. The primary outcomes for this meta-Analysis were long-Term freedom from atrial fibrillation at 12-month follow-up and overall postoperative complication rates. For all included studies, the methodological quality was assessed through the Cochrane Collaboration's tool for risk of bias. Results. A total of 247 articles were identified with eight being included in this review as they satisfied the prespecified inclusion criteria. Overall, there was no significant difference in freedom from atrial fibrillation at ≥12-month follow-up between those receiving cryoballoon and radiofrequency ablation, respectively (OR = 0.98, CI = 0.67-1.43, I2 = 56, p=0.90). Additionally, the secondary outcomes of duration of ablation, fluoroscopy time, and ablation time failed to reach significance. Cryoballoon ablation had significantly greater odds of postoperative phrenic nerve injury at 12-month follow-up. Conclusions. Our meta-Analysis suggests that cryoballoon ablation provides comparable benefits with regard to freedom from atrial fibrillation at medium-Term follow-up, fluoroscopy time, ablation time, operative duration, and overall complication rate in comparison to radiofrequency ablation.
AB - Background. Pulmonary vein isolation is commonly performed using radiofrequency energy with cryoablation gaining acceptance. We performed a meta-Analysis of randomized controlled trials which compared radiofrequency versus cryoablation for patients with atrial fibrillation. Methods. A systematic search strategy identified both published and unpublished articles from inception to November 10, 2016, in multiple databases. The primary outcomes for this meta-Analysis were long-Term freedom from atrial fibrillation at 12-month follow-up and overall postoperative complication rates. For all included studies, the methodological quality was assessed through the Cochrane Collaboration's tool for risk of bias. Results. A total of 247 articles were identified with eight being included in this review as they satisfied the prespecified inclusion criteria. Overall, there was no significant difference in freedom from atrial fibrillation at ≥12-month follow-up between those receiving cryoballoon and radiofrequency ablation, respectively (OR = 0.98, CI = 0.67-1.43, I2 = 56, p=0.90). Additionally, the secondary outcomes of duration of ablation, fluoroscopy time, and ablation time failed to reach significance. Cryoballoon ablation had significantly greater odds of postoperative phrenic nerve injury at 12-month follow-up. Conclusions. Our meta-Analysis suggests that cryoballoon ablation provides comparable benefits with regard to freedom from atrial fibrillation at medium-Term follow-up, fluoroscopy time, ablation time, operative duration, and overall complication rate in comparison to radiofrequency ablation.
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U2 - 10.1155/2018/6276241
DO - 10.1155/2018/6276241
M3 - Review article
C2 - 29805800
AN - SCOPUS:85045636099
SN - 2090-8016
VL - 2018
JO - Cardiology Research and Practice
JF - Cardiology Research and Practice
M1 - 6276241
ER -