Radical cyclization strategies for the formation of ring constrained tricyclic tropane analogues

Alexander Hoepping, Clifford George, Judith Flippen-Anderson, Alan P. Kozikowski

Research output: Contribution to journalArticle

Abstract

A concise and efficient method for the construction of N, C3-constrained tropane derivatives has been developed. The key step of the reaction sequence involves either a 6- or a 7-trig radical cyclization. (C) 2000 Published by Elsevier Science Ltd.

Original languageEnglish (US)
Pages (from-to)7427-7432
Number of pages6
JournalTetrahedron Letters
Volume41
Issue number39
DOIs
StatePublished - Sep 23 2000

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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