TY - JOUR
T1 - Radiation therapy and breast cancer
AU - Gage, Irene
AU - Harris, Jay R.
PY - 1997/1/1
Y1 - 1997/1/1
N2 - Although the role of radiation therapy in the management of ductal carcinoma in situ is somewhat controversial, the benefit of radiation therapy in breast-conserving treatment of early stage invasive breast cancer is well established. Patients undergoing tumor excision with clear margins have low rates of recurrence with radiation therapy whether there is an extensive intraductal component or not. In all patients, there is a significantly higher risk of recurrence without radiation therapy. In patients receiving systemic therapy, the optimal sequence of chemotherapy and radiation therapy is still being defined; however, in patients with positive nodes and negative margins it is now clear that it is preferable to start chemotherapy first.
AB - Although the role of radiation therapy in the management of ductal carcinoma in situ is somewhat controversial, the benefit of radiation therapy in breast-conserving treatment of early stage invasive breast cancer is well established. Patients undergoing tumor excision with clear margins have low rates of recurrence with radiation therapy whether there is an extensive intraductal component or not. In all patients, there is a significantly higher risk of recurrence without radiation therapy. In patients receiving systemic therapy, the optimal sequence of chemotherapy and radiation therapy is still being defined; however, in patients with positive nodes and negative margins it is now clear that it is preferable to start chemotherapy first.
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U2 - 10.1097/00001622-199711000-00006
DO - 10.1097/00001622-199711000-00006
M3 - Review article
C2 - 9370073
AN - SCOPUS:0030726980
VL - 9
SP - 527
EP - 531
JO - Current Opinion in Oncology
JF - Current Opinion in Oncology
SN - 1040-8746
IS - 6
ER -