Racial disparities in tissue plasminogen activator treatment rate for stroke: A population-based study

Amie W. Hsia, Dorothy F. Edwards, Lewis B. Morgenstern, Jeffrey J. Wing, Nina C. Brown, Regina Coles, Sarah Loftin, Andrea Wein, Sara S. Koslosky, Sabiha Fatima, Brisa N. Sánchez, Ali Fokar, M Christopher Gibbons, Nawar Shara, Annapurni Jayam-Trouth, Chelsea S. Kidwell

Research output: Contribution to journalArticle

Abstract

Background and Purpose-Some prior studies have shown that racial disparities exist in intravenous tissue plasminogen activator (tPA) use for acute ischemic stroke. We sought to determine whether race was associated with tPA treatment for stroke in a predominantly black urban population. Methods-Systematic chart abstraction was performed on consecutive hospitalized patients with ischemic stroke from all 7 acute care hospitals in the District of Columbia from February 1, 2008, to January 31, 2009. Results-Of 1044 patients with ischemic stroke, 74% were black, 19% non-Hispanic white, and 5% received intravenous tPA. Blacks were one third less likely than whites to receive intravenous tPA (3% versus 10%, P

Original languageEnglish (US)
Pages (from-to)2217-2221
Number of pages5
JournalStroke
Volume42
Issue number8
DOIs
StatePublished - Aug 2011

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Tissue Plasminogen Activator
Stroke
Population
Urban Population
Therapeutics

Keywords

  • acute stroke
  • African American
  • disparities
  • race
  • thrombolytic therapy
  • tPA

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Clinical Neurology
  • Advanced and Specialized Nursing

Cite this

Hsia, A. W., Edwards, D. F., Morgenstern, L. B., Wing, J. J., Brown, N. C., Coles, R., ... Kidwell, C. S. (2011). Racial disparities in tissue plasminogen activator treatment rate for stroke: A population-based study. Stroke, 42(8), 2217-2221. https://doi.org/10.1161/STROKEAHA.111.613828

Racial disparities in tissue plasminogen activator treatment rate for stroke : A population-based study. / Hsia, Amie W.; Edwards, Dorothy F.; Morgenstern, Lewis B.; Wing, Jeffrey J.; Brown, Nina C.; Coles, Regina; Loftin, Sarah; Wein, Andrea; Koslosky, Sara S.; Fatima, Sabiha; Sánchez, Brisa N.; Fokar, Ali; Gibbons, M Christopher; Shara, Nawar; Jayam-Trouth, Annapurni; Kidwell, Chelsea S.

In: Stroke, Vol. 42, No. 8, 08.2011, p. 2217-2221.

Research output: Contribution to journalArticle

Hsia, AW, Edwards, DF, Morgenstern, LB, Wing, JJ, Brown, NC, Coles, R, Loftin, S, Wein, A, Koslosky, SS, Fatima, S, Sánchez, BN, Fokar, A, Gibbons, MC, Shara, N, Jayam-Trouth, A & Kidwell, CS 2011, 'Racial disparities in tissue plasminogen activator treatment rate for stroke: A population-based study', Stroke, vol. 42, no. 8, pp. 2217-2221. https://doi.org/10.1161/STROKEAHA.111.613828
Hsia, Amie W. ; Edwards, Dorothy F. ; Morgenstern, Lewis B. ; Wing, Jeffrey J. ; Brown, Nina C. ; Coles, Regina ; Loftin, Sarah ; Wein, Andrea ; Koslosky, Sara S. ; Fatima, Sabiha ; Sánchez, Brisa N. ; Fokar, Ali ; Gibbons, M Christopher ; Shara, Nawar ; Jayam-Trouth, Annapurni ; Kidwell, Chelsea S. / Racial disparities in tissue plasminogen activator treatment rate for stroke : A population-based study. In: Stroke. 2011 ; Vol. 42, No. 8. pp. 2217-2221.
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