Racial disparities in maternal and neonatal outcomes in HIV-1 positive mothers

Laura Parikh, Julia Timofeev, Jasbir Singh, Shannon Sullivan, Chun Chih Huang, Helain J. Landy, Rita Wesley Driggers

Research output: Contribution to journalArticle

Abstract

Objective To compare obstetric and neonatal outcomes between human immunodeficiency virus (HIV) positive (HIV+) and HIV negative (HIV-) women and to determine if racial disparities exist among pregnancies complicated by HIV infection. Study Design This was a retrospective analysis of data from the Consortium of Safe Labor between 2002 and 2008. Comparisons of obstetric morbidity, neonatal morbidity, and indications for cesarean delivery were examined. Included were singletons with documented HIV status, race, and antepartum admission. Chi-square, Fisher exact tests, and logistic regression were used for statistical analysis. Results Included were 178,972 patients (178,210 HIV-, 762 HIV+, 464 HIV+ black, 298 HIV+ nonblack). HIV+ women were more likely to have a cesarean delivery, preterm premature rupture of membranes, another sexually transmitted infection, and delivery at an earlier gestational age. Obstetric outcomes were similar between HIV+ black and HIV+ nonblack women. Neonates of HIV+ mothers had lower birth weights and higher rates of neonatal intensive care admissions. HIV+ black women had lower birth weight neonates than HIV+ nonblack women. Conclusion HIV+ women have higher rates of obstetric complications and deliver at an earlier gestational age than HIV- mothers. Lower birth weight was the only notable complication among HIV+ black women compared with HIV+ nonblack women.

Original languageEnglish (US)
Pages (from-to)513-520
Number of pages8
JournalAmerican Journal of Perinatology
Volume31
Issue number6
DOIs
StatePublished - 2014
Externally publishedYes

Fingerprint

HIV-1
Mothers
HIV
Obstetrics
Birth Weight
Gestational Age
Newborn Infant
Morbidity
Neonatal Intensive Care
Virus Diseases
Sexually Transmitted Diseases

Keywords

  • HIV
  • maternal morbidity
  • neonatal morbidity
  • pregnancy

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology
  • Medicine(all)

Cite this

Racial disparities in maternal and neonatal outcomes in HIV-1 positive mothers. / Parikh, Laura; Timofeev, Julia; Singh, Jasbir; Sullivan, Shannon; Huang, Chun Chih; Landy, Helain J.; Driggers, Rita Wesley.

In: American Journal of Perinatology, Vol. 31, No. 6, 2014, p. 513-520.

Research output: Contribution to journalArticle

Parikh, Laura ; Timofeev, Julia ; Singh, Jasbir ; Sullivan, Shannon ; Huang, Chun Chih ; Landy, Helain J. ; Driggers, Rita Wesley. / Racial disparities in maternal and neonatal outcomes in HIV-1 positive mothers. In: American Journal of Perinatology. 2014 ; Vol. 31, No. 6. pp. 513-520.
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KW - maternal morbidity

KW - neonatal morbidity

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