Racial differences in completion of the living kidney donor evaluation process

Komal Kumar, James M. Tonascia, Abimereki D. Muzaale, Tanjala S. Purnell, Shane E. Ottmann, Fawaz Al Ammary, Mary G. Bowring, Anna Poon, Elizabeth A. King, Allan B. Massie, Eric K.H. Chow, Alvin G. Thomas, Hao Ying, Marvin Borja, Jonathan M. Konel, Macey Henderson, Andrew M. Cameron, Jacqueline M. Garonzik-Wang, Dorry L. Segev

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Racial disparities in living donor kidney transplantation (LDKT) persist but the most effective target to eliminate these disparities remains unknown. One potential target could be delays during completion of the live donor evaluation process. We studied racial differences in progression through the evaluation process for 247 African American (AA) and 664 non-AA living donor candidates at our center between January 2011 and March 2015. AA candidates were more likely to be obese (38% vs 22%: P <.001), biologically related (66% vs 44%: P <.001), and live ≤50 miles from the center (64% vs 37%: P <.001) than non-AAs. Even after adjusting for these differences, AAs were less likely to progress from referral to donation (aHR for AA vs non-AA: 0.260.47 0.83; P =.01). We then assessed racial differences in completion of each step of the evaluation process and found disparities in progression from medical screening to in-person evaluation (aHR: 0.410.620.94; P =.02) and from clearance to donation (aHR: 0.28 0.510.91; P =.02), compared with from referral to medical screening (aHR: 0.781.021.33; P =.95) and from in-person evaluation to clearance (aHR: 0.59 0.931.44; P =.54). Delays may be a manifestation of the transplant candidate's social network, thus, targeted efforts to optimize networks for identification of donor candidates may help address LDKT disparities.

Original languageEnglish (US)
Article numbere13291
JournalClinical Transplantation
Volume32
Issue number7
DOIs
StatePublished - Jul 2018

Keywords

  • donor candidates
  • listed candidates
  • living donation

ASJC Scopus subject areas

  • Transplantation

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