Race, ethnicity and benign prostatic hyperplasia in the health professionals follow-up study

Elizabeth A Platz, Ichiro Kawachi, Eric B. Rimm, Walter C. Willett, Edward Giovannucci

Research output: Contribution to journalArticle

Abstract

Purpose: We examined whether the prevalence of benign prostatic hyperplasia (BPH) varies by racial or ethnic origin in a large cohort of American male health professionals. Materials and Methods: Included in our study were 1,508 men who underwent surgery for BPH between 1986 and 1994, and 1,837 with high moderate to severe lower urinary tract symptoms assessed by the American Urological Association symptom index in 1992 or 1994. 'Noncases' comprised 23,246 asymptomatic participants. Self-reported major ancestry was black in 201 men, Asian in 413, other origin in 604 and white in 25,373. White heritage was further classified as southern European in 6,408 men, Scandinavian in 2,951 and other white in 16,014. The relative risk of BPH and 95% confidence intervals (CI) adjusted for age, body mass index, alcohol consumption, smoking and physical activity were calculated by logistic regression. Results: Black men were not at increased risk for BPH (relative risk 0.85, 95% CI 0.55 to 1.31) compared with white men. Asian men were less likely to have undergone BPH surgery (relative risk 0.41, 95% CI 0.21 to 0.82), although the relative risk for symptoms was similar to that of white men. White men whose major ancestry was southern European were at modestly higher risk for BPH surgery (relative risk 1.28, 95% CI 1.12 to 1.46) and symptoms (relative risk 1.34, 95% CI 1.20 to 1.50), whereas men of Scandinavian heritage were at slightly decreased risk for symptoms than those of other white heritages. Conclusions: Racial and ethnic variation is evident in the incidence of BPH surgery and symptom severity. Whether this observed variation reflects underlying biological phenomena rather than differences in symptom tolerance requires further exploration.

Original languageEnglish (US)
Pages (from-to)490-495
Number of pages6
JournalJournal of Urology
Volume163
Issue number2
StatePublished - Feb 2000

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Prostatic Hyperplasia
Health
Confidence Intervals
Biological Phenomena
Lower Urinary Tract Symptoms
Alcohol Drinking
Body Mass Index
Logistic Models
Smoking
Exercise
Incidence

Keywords

  • Ethnic groups
  • Prostate
  • Prostatic hyperplasia
  • Racial stocks
  • Risk factors

ASJC Scopus subject areas

  • Urology

Cite this

Platz, E. A., Kawachi, I., Rimm, E. B., Willett, W. C., & Giovannucci, E. (2000). Race, ethnicity and benign prostatic hyperplasia in the health professionals follow-up study. Journal of Urology, 163(2), 490-495.

Race, ethnicity and benign prostatic hyperplasia in the health professionals follow-up study. / Platz, Elizabeth A; Kawachi, Ichiro; Rimm, Eric B.; Willett, Walter C.; Giovannucci, Edward.

In: Journal of Urology, Vol. 163, No. 2, 02.2000, p. 490-495.

Research output: Contribution to journalArticle

Platz, EA, Kawachi, I, Rimm, EB, Willett, WC & Giovannucci, E 2000, 'Race, ethnicity and benign prostatic hyperplasia in the health professionals follow-up study', Journal of Urology, vol. 163, no. 2, pp. 490-495.
Platz, Elizabeth A ; Kawachi, Ichiro ; Rimm, Eric B. ; Willett, Walter C. ; Giovannucci, Edward. / Race, ethnicity and benign prostatic hyperplasia in the health professionals follow-up study. In: Journal of Urology. 2000 ; Vol. 163, No. 2. pp. 490-495.
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abstract = "Purpose: We examined whether the prevalence of benign prostatic hyperplasia (BPH) varies by racial or ethnic origin in a large cohort of American male health professionals. Materials and Methods: Included in our study were 1,508 men who underwent surgery for BPH between 1986 and 1994, and 1,837 with high moderate to severe lower urinary tract symptoms assessed by the American Urological Association symptom index in 1992 or 1994. 'Noncases' comprised 23,246 asymptomatic participants. Self-reported major ancestry was black in 201 men, Asian in 413, other origin in 604 and white in 25,373. White heritage was further classified as southern European in 6,408 men, Scandinavian in 2,951 and other white in 16,014. The relative risk of BPH and 95{\%} confidence intervals (CI) adjusted for age, body mass index, alcohol consumption, smoking and physical activity were calculated by logistic regression. Results: Black men were not at increased risk for BPH (relative risk 0.85, 95{\%} CI 0.55 to 1.31) compared with white men. Asian men were less likely to have undergone BPH surgery (relative risk 0.41, 95{\%} CI 0.21 to 0.82), although the relative risk for symptoms was similar to that of white men. White men whose major ancestry was southern European were at modestly higher risk for BPH surgery (relative risk 1.28, 95{\%} CI 1.12 to 1.46) and symptoms (relative risk 1.34, 95{\%} CI 1.20 to 1.50), whereas men of Scandinavian heritage were at slightly decreased risk for symptoms than those of other white heritages. Conclusions: Racial and ethnic variation is evident in the incidence of BPH surgery and symptom severity. Whether this observed variation reflects underlying biological phenomena rather than differences in symptom tolerance requires further exploration.",
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N2 - Purpose: We examined whether the prevalence of benign prostatic hyperplasia (BPH) varies by racial or ethnic origin in a large cohort of American male health professionals. Materials and Methods: Included in our study were 1,508 men who underwent surgery for BPH between 1986 and 1994, and 1,837 with high moderate to severe lower urinary tract symptoms assessed by the American Urological Association symptom index in 1992 or 1994. 'Noncases' comprised 23,246 asymptomatic participants. Self-reported major ancestry was black in 201 men, Asian in 413, other origin in 604 and white in 25,373. White heritage was further classified as southern European in 6,408 men, Scandinavian in 2,951 and other white in 16,014. The relative risk of BPH and 95% confidence intervals (CI) adjusted for age, body mass index, alcohol consumption, smoking and physical activity were calculated by logistic regression. Results: Black men were not at increased risk for BPH (relative risk 0.85, 95% CI 0.55 to 1.31) compared with white men. Asian men were less likely to have undergone BPH surgery (relative risk 0.41, 95% CI 0.21 to 0.82), although the relative risk for symptoms was similar to that of white men. White men whose major ancestry was southern European were at modestly higher risk for BPH surgery (relative risk 1.28, 95% CI 1.12 to 1.46) and symptoms (relative risk 1.34, 95% CI 1.20 to 1.50), whereas men of Scandinavian heritage were at slightly decreased risk for symptoms than those of other white heritages. Conclusions: Racial and ethnic variation is evident in the incidence of BPH surgery and symptom severity. Whether this observed variation reflects underlying biological phenomena rather than differences in symptom tolerance requires further exploration.

AB - Purpose: We examined whether the prevalence of benign prostatic hyperplasia (BPH) varies by racial or ethnic origin in a large cohort of American male health professionals. Materials and Methods: Included in our study were 1,508 men who underwent surgery for BPH between 1986 and 1994, and 1,837 with high moderate to severe lower urinary tract symptoms assessed by the American Urological Association symptom index in 1992 or 1994. 'Noncases' comprised 23,246 asymptomatic participants. Self-reported major ancestry was black in 201 men, Asian in 413, other origin in 604 and white in 25,373. White heritage was further classified as southern European in 6,408 men, Scandinavian in 2,951 and other white in 16,014. The relative risk of BPH and 95% confidence intervals (CI) adjusted for age, body mass index, alcohol consumption, smoking and physical activity were calculated by logistic regression. Results: Black men were not at increased risk for BPH (relative risk 0.85, 95% CI 0.55 to 1.31) compared with white men. Asian men were less likely to have undergone BPH surgery (relative risk 0.41, 95% CI 0.21 to 0.82), although the relative risk for symptoms was similar to that of white men. White men whose major ancestry was southern European were at modestly higher risk for BPH surgery (relative risk 1.28, 95% CI 1.12 to 1.46) and symptoms (relative risk 1.34, 95% CI 1.20 to 1.50), whereas men of Scandinavian heritage were at slightly decreased risk for symptoms than those of other white heritages. Conclusions: Racial and ethnic variation is evident in the incidence of BPH surgery and symptom severity. Whether this observed variation reflects underlying biological phenomena rather than differences in symptom tolerance requires further exploration.

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