Quantitative Systems Pharmacology for Neuroscience Drug Discovery and Development: Current Status, Opportunities, and Challenges

Medicine & Life Sciences

• Neurosciences 66%
• Drug Discovery 64%
• Drug Development 59%
• Pharmacology 41%
• Central Nervous System Diseases 34%
• Central Nervous System Agents 29%
• Education 26%
• Central Nervous System 23%
• National Institute on Drug Abuse (U.S.) 17%
• National Institute on Aging (U.S.) 16%
• National Institute of Neurological Disorders and Stroke (U.S.) 15%
• Brain 15%
• Pharmaceutical Research 14%
• National Institute of Mental Health (U.S.) 14%
• Pharmacokinetics 7%
• Clinical Trials 6%
• Biomarkers 6%
• Inflammation 6%
• Therapeutics 5%
• Pharmaceutical Preparations 4%

Mathematics

• Drug Discovery 100%
• Pharmacology 93%
• Neuroscience 80%
• Drugs 16%
• Disorder 14%
• Brain 13%
• Inflammation 6%
• Computational Neuroscience 6%
• Pharmacodynamics 6%
• Essential Component 5%
• Oncology 5%
• Research and Development 5%
• Stroke 5%
• Pharmaceuticals 5%
• Biomarkers 5%
• Exploitation 5%
• Collaboration 5%
• Pharmacokinetics 5%
• Pathway 4%
• Biological Systems 4%
• Accelerate 4%
• Health 4%
• Clinical Trials 3%
• Target 3%
• Evaluate 3%
• Interaction 2%
• Modeling 2%
• Design 2%
• Relationships 2%

Engineering & Materials Science

• Drug Development 88%
• Drug Discovery 83%
• Neurology 73%
• Brain 19%
• Pharmacodynamics 12%
• Computational neuroscience 12%
• Pharmacokinetics 11%
• Oncology 10%
• Biomarkers 9%
• Biological systems 8%
• Networks (circuits) 8%
• Drug products 8%
• Aging of materials 6%
• Health 5%