Quantitative determination of prostatic epithelial and stromal hyperplasia by a new technique. Biomorphometrics

D. P. DeKlerk, D. S. Coffey

Research output: Contribution to journalArticle

Abstract

Recent studies of neonatal and pathologic growth of the prostate have postulated the possible importance of stromal-epithelial interaction in the control of prostatic growth. To allow further analysis of the possible importance of this interaction, a new technique has been developed that permits quantification of the total number of stromal and epithelial cells in the prostate gland. This technique has been termed biomorphometrics and is a combination of standard morphometric and biochemical methodology. This method has been applied to analyze the hormonal response of the stromal and epithelial cells of the rat ventral prostate.

Original languageEnglish (US)
Pages (from-to)240-245
Number of pages6
JournalInvestigative urology
Volume16
Issue number3
StatePublished - Dec 1 1978

ASJC Scopus subject areas

  • Medicine(all)

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