Quantitative bacillary response to treatment in Mycobacterium tuberculosis infected and M. africanum infected adults with pulmonary tuberculosis

M. L. Joloba, J. L. Johnson, A. Namale, A. Morrissey, A. E. Assegghai, S. Rüsch-Gerdes, R. D. Mugerwa, J. J. Ellner, K. D. Eisenach

Research output: Contribution to journalArticle

Abstract

Data regarding possible differences in microbiological response to therapy of disease caused by Mycobacterium tuberculosis and M. africanum are limited. Presenting clinical characteristics and sputum bacillary load during standard short-course chemotherapy in patients with newly-diagnosed pulmonary tuberculosis due to M. tuberculosis (n = 7) and M. africanum (n = 6) were compared. Changes in sputum bacillary load were measured using quantitative acid-fast bacilli smears, colony forming unit assay, and time until positive culture in the BACTEC® radiometric system. Presentation and response to short course chemotherapy were comparable between patients infected with M. tuberculosis and those infected with M. africanum.

Original languageEnglish (US)
Pages (from-to)579-582
Number of pages4
JournalInternational Journal of Tuberculosis and Lung Disease
Volume5
Issue number6
Publication statusPublished - 2001
Externally publishedYes

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Keywords

  • Chemotherapy
  • Colony forming units
  • M. africanum
  • Mycobacterium tuberculosis
  • Radiometric
  • Tuberculosis

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Joloba, M. L., Johnson, J. L., Namale, A., Morrissey, A., Assegghai, A. E., Rüsch-Gerdes, S., ... Eisenach, K. D. (2001). Quantitative bacillary response to treatment in Mycobacterium tuberculosis infected and M. africanum infected adults with pulmonary tuberculosis. International Journal of Tuberculosis and Lung Disease, 5(6), 579-582.