Quantitative analysis on electrooculography (EOG) for neurodegenerative disease

Chang Chia Liu, W. Art Chaovalitwongse, Panos M. Pardalos, Onur Seref, Petros Xanthopoulos, J. C. Sackellares, Frank M. Skidmore

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Many studies have documented abnormal horizontal and vertical eye movements in human neurodegenerative disease as well as during altered states of consciousness (including drowsiness and intoxication) in healthy adults. Eye movement measurement may play an important role measuring the progress of neurodegenerative diseases and state of alertness in healthy individuals. There are several techniques for measuring eye movement, Infrared detection technique (IR), Video-oculography (VOG), Scleral eye coil and EOG. Among those available recording techniques, EOG is a major source for monitoring the abnormal eye movement. In this real-time quantitative analysis study, the methods which can capture the characteristic of the eye movement were proposed to accurately categorize the state of neurodegenerative subjects. The EOG recordings were taken while 5 tested subjects were watching a short (>120s) animation clip. In response to the animated clip the participants executed a number of eye movements, including vertical smooth pursued (SVP), horizontal smooth pursued (HVP) and random saccades (RS). Detection of abnormalities in ocular movement may improve our diagnosis and understanding a neurodegenerative disease and altered states of consciousness. A standard real-time quantitative analysis will improve detection and provide a better understanding of pathology in these disorders.

Original languageEnglish (US)
Title of host publicationData Mining, Systems Analysis, and Optimization in Biomedicine
Pages246-253
Number of pages8
DOIs
StatePublished - Dec 1 2007
EventConference on Data Mining, Systems Analysis, and Optimization in Biomedicine, 2007 - Gainesville, FL, United States
Duration: Mar 28 2007Mar 30 2007

Publication series

NameAIP Conference Proceedings
Volume953
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Other

OtherConference on Data Mining, Systems Analysis, and Optimization in Biomedicine, 2007
CountryUnited States
CityGainesville, FL
Period3/28/073/30/07

Keywords

  • Electro-oculography
  • Eye movement
  • Motor fluctuation
  • Parkinson disease

ASJC Scopus subject areas

  • Physics and Astronomy(all)

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