Quantitative analysis of a urine-based assay for detection of lipoarabinomannan in patients with tuberculosis

Maunank Shah; Neil A. Martinson; Richard E. Chaisson; Desmond J. Martin; Ebrahim Variava; Susan E. Dorman

doi:10.1128/JCM.00363-10

Quantitative analysis of a urine-based assay for detection of lipoarabinomannan in patients with tuberculosis

Maunank Shah, Neil A. Martinson, Richard E. Chaisson, Desmond J. Martin, Ebrahim Variava, Susan E. Dorman

School of Medicine

Research output: Contribution to journal › Article › peer-review

57 Scopus citations

Abstract

Urinary lipoarabinomannan (LAM) detection is a promising approach for rapid diagnosis of active tuberculosis (TB). In microbiologically confirmed TB patients, quantitative LAM detection results increased progressively with bacillary burden and immunosuppression. Patients with disseminated TB and/or advanced HIV are target populations for whom urine LAM detection may be particularly useful.

Original language	English (US)
Pages (from-to)	2972-2974
Number of pages	3
Journal	Journal of clinical microbiology
Volume	48
Issue number	8
DOIs	https://doi.org/10.1128/JCM.00363-10
State	Published - Aug 2010

ASJC Scopus subject areas

Microbiology (medical)

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title = "Quantitative analysis of a urine-based assay for detection of lipoarabinomannan in patients with tuberculosis",

abstract = "Urinary lipoarabinomannan (LAM) detection is a promising approach for rapid diagnosis of active tuberculosis (TB). In microbiologically confirmed TB patients, quantitative LAM detection results increased progressively with bacillary burden and immunosuppression. Patients with disseminated TB and/or advanced HIV are target populations for whom urine LAM detection may be particularly useful.",

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AU - Variava, Ebrahim

AU - Dorman, Susan E.

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AB - Urinary lipoarabinomannan (LAM) detection is a promising approach for rapid diagnosis of active tuberculosis (TB). In microbiologically confirmed TB patients, quantitative LAM detection results increased progressively with bacillary burden and immunosuppression. Patients with disseminated TB and/or advanced HIV are target populations for whom urine LAM detection may be particularly useful.

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Quantitative analysis of a urine-based assay for detection of lipoarabinomannan in patients with tuberculosis

Abstract

ASJC Scopus subject areas

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