Quantitative analysis of a urine-based assay for detection of lipoarabinomannan in patients with tuberculosis

Maunank Shah, Neil A. Martinson, Richard E. Chaisson, Desmond J. Martin, Ebrahim Variava, Susan E. Dorman

Research output: Contribution to journalArticle

Abstract

Urinary lipoarabinomannan (LAM) detection is a promising approach for rapid diagnosis of active tuberculosis (TB). In microbiologically confirmed TB patients, quantitative LAM detection results increased progressively with bacillary burden and immunosuppression. Patients with disseminated TB and/or advanced HIV are target populations for whom urine LAM detection may be particularly useful.

Original languageEnglish (US)
Pages (from-to)2972-2974
Number of pages3
JournalJournal of clinical microbiology
Volume48
Issue number8
DOIs
StatePublished - Aug 1 2010

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ASJC Scopus subject areas

  • Microbiology (medical)

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