TY - JOUR
T1 - Quantification of coronary artery volume flow rate using fast velocity- encoded cine MR imaging
AU - Sakuma, Hajime
AU - Saeed, Maythem
AU - Takeda, Kan
AU - Wendland, Michael F.
AU - Schwitter, Juerg
AU - Szolar, Dieter H.
AU - Derugin, Nikita
AU - Shimakawa, Ann
AU - Foo, Thomas K F
AU - Higgins, Charles B.
PY - 1997/5
Y1 - 1997/5
N2 - OBJECTIVE. Breath-hold velocity-encoded cine (VENC) MR imaging has been proposed as a method for measuring coronary blood flow. However, most studies have measured velocity rather than volume flow rate in the coronary arteries. The purpose of this study was to measure volume flow rate in the coronary artery of dogs using high-speed gradients and to compare MR flow measurements with those obtained with a sonographic flowmeter. MATERIALS AND METHODS. Fast VENC MR images were obtained with a high-speed-gradient 1.5-T MR system in seven anesthetized dogs before and after administration of dipyridamole. Images were acquired on double oblique planes perpendicular to the left anterior descending arteries with a slice thickness of 5 mm, a field of view of 20 x 10 cm, a velocity window of ±1 m/sec, an average imaging time of 21 sec, a TR/TE of 11/5, and a temporal resolution of 44 msec. RESULTS. Coronary flow measured with VENC MR imaging correlated well with flow measured by the flowmeter (r = .95, slope = 0.97, n = 88). Interobserver variability in measuring coronary flow volume was 8%. CONCLUSION. Fast VENC MR imaging with high-speed gradients can provide accurate quantification of volume flow rate in coronary arteries.
AB - OBJECTIVE. Breath-hold velocity-encoded cine (VENC) MR imaging has been proposed as a method for measuring coronary blood flow. However, most studies have measured velocity rather than volume flow rate in the coronary arteries. The purpose of this study was to measure volume flow rate in the coronary artery of dogs using high-speed gradients and to compare MR flow measurements with those obtained with a sonographic flowmeter. MATERIALS AND METHODS. Fast VENC MR images were obtained with a high-speed-gradient 1.5-T MR system in seven anesthetized dogs before and after administration of dipyridamole. Images were acquired on double oblique planes perpendicular to the left anterior descending arteries with a slice thickness of 5 mm, a field of view of 20 x 10 cm, a velocity window of ±1 m/sec, an average imaging time of 21 sec, a TR/TE of 11/5, and a temporal resolution of 44 msec. RESULTS. Coronary flow measured with VENC MR imaging correlated well with flow measured by the flowmeter (r = .95, slope = 0.97, n = 88). Interobserver variability in measuring coronary flow volume was 8%. CONCLUSION. Fast VENC MR imaging with high-speed gradients can provide accurate quantification of volume flow rate in coronary arteries.
UR - http://www.scopus.com/inward/record.url?scp=0030999026&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0030999026&partnerID=8YFLogxK
M3 - Article
C2 - 9129446
AN - SCOPUS:0030999026
SN - 0361-803X
VL - 168
SP - 1363
EP - 1367
JO - The American journal of roentgenology and radium therapy
JF - The American journal of roentgenology and radium therapy
IS - 5
ER -