Quantification of coronary artery volume flow rate using fast velocity- encoded cine MR imaging

Hajime Sakuma, Maythem Saeed, Kan Takeda, Michael F. Wendland, Juerg Schwitter, Dieter H. Szolar, Nikita Derugin, Ann Shimakawa, Thomas K F Foo, Charles B. Higgins

Research output: Contribution to journalArticlepeer-review

35 Scopus citations


OBJECTIVE. Breath-hold velocity-encoded cine (VENC) MR imaging has been proposed as a method for measuring coronary blood flow. However, most studies have measured velocity rather than volume flow rate in the coronary arteries. The purpose of this study was to measure volume flow rate in the coronary artery of dogs using high-speed gradients and to compare MR flow measurements with those obtained with a sonographic flowmeter. MATERIALS AND METHODS. Fast VENC MR images were obtained with a high-speed-gradient 1.5-T MR system in seven anesthetized dogs before and after administration of dipyridamole. Images were acquired on double oblique planes perpendicular to the left anterior descending arteries with a slice thickness of 5 mm, a field of view of 20 x 10 cm, a velocity window of ±1 m/sec, an average imaging time of 21 sec, a TR/TE of 11/5, and a temporal resolution of 44 msec. RESULTS. Coronary flow measured with VENC MR imaging correlated well with flow measured by the flowmeter (r = .95, slope = 0.97, n = 88). Interobserver variability in measuring coronary flow volume was 8%. CONCLUSION. Fast VENC MR imaging with high-speed gradients can provide accurate quantification of volume flow rate in coronary arteries.

Original languageEnglish (US)
Pages (from-to)1363-1367
Number of pages5
JournalAmerican Journal of Roentgenology
Issue number5
StatePublished - May 1997
Externally publishedYes

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology


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