Quality of life after stroke: A prospective longitudinal study

William E. Haley; David L. Roth; Brett Kissela; Martinique Perkins; George Howard

doi:10.1007/s11136-010-9810-6

Quality of life after stroke: A prospective longitudinal study

William E. Haley, David L. Roth, Brett Kissela, Martinique Perkins, George Howard

Research output: Contribution to journal › Article › peer-review

73 Scopus citations

Abstract

Purpose: To measure the impact of stroke on quality of life (QOL), and analyze whether race, gender, age, income, or living alone moderated those changes, using prospective longitudinal methods. Methods: Participants in the REasons for Geographic and Racial Differences in Stroke study without history of stroke completed baseline SF-12 Mental (MCS) and Physical Component Summary (PCS) measures and a depression scale. Measures were repeated (M = 1231 days later) by 136 participants after an incident medically documented stroke and by 136 demographically matched stroke-free controls. Results: Stroke participants showed significant worsening than controls in all three QOL measures. Controls also declined significantly in PCS. Standardized effect sizes for stroke versus control participants after adjusting for covariates were similar across the three measures and ranged from .366 to .465 standard deviation units. Stroke survivors who lived alone were at greater risk for increases in depressive symptoms. Conclusions: Multiple declines in QOL occur after stroke, and social isolation heightens risk for increasing depression after stroke. Our prospective design and use of a population-based sample with matched controls suggests similar effects in both physical health and mental health QOL domains and offers unique strengths in understanding the impact of stroke on QOL.

Original language	English (US)
Pages (from-to)	799-806
Number of pages	8
Journal	Quality of Life Research
Volume	20
Issue number	6
DOIs	https://doi.org/10.1007/s11136-010-9810-6
State	Published - Aug 2011
Externally published	Yes

Keywords

Population-based studies
Quality of life
Stroke

ASJC Scopus subject areas

Public Health, Environmental and Occupational Health

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10.1007/s11136-010-9810-6

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@article{79c7888f7c5642a28d817387728348d9,

title = "Quality of life after stroke: A prospective longitudinal study",

abstract = "Purpose: To measure the impact of stroke on quality of life (QOL), and analyze whether race, gender, age, income, or living alone moderated those changes, using prospective longitudinal methods. Methods: Participants in the REasons for Geographic and Racial Differences in Stroke study without history of stroke completed baseline SF-12 Mental (MCS) and Physical Component Summary (PCS) measures and a depression scale. Measures were repeated (M = 1231 days later) by 136 participants after an incident medically documented stroke and by 136 demographically matched stroke-free controls. Results: Stroke participants showed significant worsening than controls in all three QOL measures. Controls also declined significantly in PCS. Standardized effect sizes for stroke versus control participants after adjusting for covariates were similar across the three measures and ranged from .366 to .465 standard deviation units. Stroke survivors who lived alone were at greater risk for increases in depressive symptoms. Conclusions: Multiple declines in QOL occur after stroke, and social isolation heightens risk for increasing depression after stroke. Our prospective design and use of a population-based sample with matched controls suggests similar effects in both physical health and mental health QOL domains and offers unique strengths in understanding the impact of stroke on QOL.",

keywords = "Population-based studies, Quality of life, Stroke",

author = "Haley, {William E.} and Roth, {David L.} and Brett Kissela and Martinique Perkins and George Howard",

note = "Funding Information: Acknowledgments The research reported in this paper was supported by an investigator-initiated grant (R01 NS045789, David L. Roth, PI) and by a cooperative agreement (U01 NS041588) from the National Institute of Neurological Disorders and Stroke, National Institutes of Health, Department of Health and Human Services. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute of Neurological Disorders and Stroke or the National Institutes of Health. Representatives of the funding agency have been involved in the review of the manuscript but not directly involved in the collection, management, analysis, or interpretation of the data. The authors thank the other investigators, the staff, and the participants of the REGARDS study for their valuable contributions. A full list of participating REGARDS investigators and institutions can be found at http://www.regardsstudy.org. The authors also gratefully acknowledge the contributions of Michelle Henry for conducting data collection interviews and Martha Hovater for assistance with the statistical analyses.",

year = "2011",

month = aug,

doi = "10.1007/s11136-010-9810-6",

language = "English (US)",

volume = "20",

pages = "799--806",

journal = "Quality of Life Research",

issn = "0962-9343",

publisher = "Springer Netherlands",

number = "6",

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TY - JOUR

T1 - Quality of life after stroke

T2 - A prospective longitudinal study

AU - Haley, William E.

AU - Roth, David L.

AU - Kissela, Brett

AU - Perkins, Martinique

AU - Howard, George

N1 - Funding Information: Acknowledgments The research reported in this paper was supported by an investigator-initiated grant (R01 NS045789, David L. Roth, PI) and by a cooperative agreement (U01 NS041588) from the National Institute of Neurological Disorders and Stroke, National Institutes of Health, Department of Health and Human Services. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute of Neurological Disorders and Stroke or the National Institutes of Health. Representatives of the funding agency have been involved in the review of the manuscript but not directly involved in the collection, management, analysis, or interpretation of the data. The authors thank the other investigators, the staff, and the participants of the REGARDS study for their valuable contributions. A full list of participating REGARDS investigators and institutions can be found at http://www.regardsstudy.org. The authors also gratefully acknowledge the contributions of Michelle Henry for conducting data collection interviews and Martha Hovater for assistance with the statistical analyses.

PY - 2011/8

Y1 - 2011/8

N2 - Purpose: To measure the impact of stroke on quality of life (QOL), and analyze whether race, gender, age, income, or living alone moderated those changes, using prospective longitudinal methods. Methods: Participants in the REasons for Geographic and Racial Differences in Stroke study without history of stroke completed baseline SF-12 Mental (MCS) and Physical Component Summary (PCS) measures and a depression scale. Measures were repeated (M = 1231 days later) by 136 participants after an incident medically documented stroke and by 136 demographically matched stroke-free controls. Results: Stroke participants showed significant worsening than controls in all three QOL measures. Controls also declined significantly in PCS. Standardized effect sizes for stroke versus control participants after adjusting for covariates were similar across the three measures and ranged from .366 to .465 standard deviation units. Stroke survivors who lived alone were at greater risk for increases in depressive symptoms. Conclusions: Multiple declines in QOL occur after stroke, and social isolation heightens risk for increasing depression after stroke. Our prospective design and use of a population-based sample with matched controls suggests similar effects in both physical health and mental health QOL domains and offers unique strengths in understanding the impact of stroke on QOL.

AB - Purpose: To measure the impact of stroke on quality of life (QOL), and analyze whether race, gender, age, income, or living alone moderated those changes, using prospective longitudinal methods. Methods: Participants in the REasons for Geographic and Racial Differences in Stroke study without history of stroke completed baseline SF-12 Mental (MCS) and Physical Component Summary (PCS) measures and a depression scale. Measures were repeated (M = 1231 days later) by 136 participants after an incident medically documented stroke and by 136 demographically matched stroke-free controls. Results: Stroke participants showed significant worsening than controls in all three QOL measures. Controls also declined significantly in PCS. Standardized effect sizes for stroke versus control participants after adjusting for covariates were similar across the three measures and ranged from .366 to .465 standard deviation units. Stroke survivors who lived alone were at greater risk for increases in depressive symptoms. Conclusions: Multiple declines in QOL occur after stroke, and social isolation heightens risk for increasing depression after stroke. Our prospective design and use of a population-based sample with matched controls suggests similar effects in both physical health and mental health QOL domains and offers unique strengths in understanding the impact of stroke on QOL.

KW - Population-based studies

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JO - Quality of Life Research

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Quality of life after stroke: A prospective longitudinal study

Abstract

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