Quality of HbA1c Measurement in Trinidad and Tobago

Maynika V. Rastogi, Paul Ladenson, David E. Goldstein, Randie R. Little

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Monitoring of HbA1c is the standard of care to assess diabetes control. In Trinidad & Tobago (T&T) there are no existing data on the quality of HbA1c measurement. Our study examined the precision and accuracy of HbA1c testing in T&T. Methods: Sets of 10 samples containing blinded duplicates were shipped to laboratories in T&T. This exercise was repeated 6 months later. Precision and accuracy were estimated for each laboratory/method. Results: T&T methods included immunoassay, capillary electrophoresis, and boronate affinity binding. Most, but not all, laboratories demonstrated acceptable precision and accuracy. Conclusions: Continuous oversight of HbA1c testing (eg, through proficiency testing) in T&T is recommended. These results highlight the lack of oversight of HbA1c testing in some developing countries.

Original languageEnglish (US)
Pages (from-to)768-771
Number of pages4
JournalJournal of Diabetes Science and Technology
Volume10
Issue number3
DOIs
StatePublished - May 1 2016

Keywords

  • HbA1c
  • comparison
  • glycated hemoglobin
  • proficiency testing

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Bioengineering
  • Biomedical Engineering

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