Quadrupling muscle mass in mice by targeting TGF-β signaling pathways

Agriculture & Biology

• myostatin 98%
• muscles 46%
• mice 40%
• transgenes 20%
• transforming growth factors 9%
• loss-of-function mutation 8%
• skeletal muscle 6%
• binding proteins 6%
• mechanism of action 6%
• therapeutics 5%
• dogs 5%
• sheep 4%
• mutation 4%
• cattle 4%
• genes 2%

Medicine & Life Sciences

• Myostatin 100%
• Muscles 42%
• Follistatin 30%
• Transgenes 21%
• Mothers 8%
• Loss of Function Mutation 7%
• Transforming Growth Factors 7%
• Growth 7%
• Sheep 6%
• Carrier Proteins 5%
• Psychological Inhibition 5%
• Cattle 5%
• Skeletal Muscle 5%
• Dogs 5%
• Mutation 3%
• Genes 2%
• Therapeutics 1%

Chemical Compounds

• Mutation 39%
• Amount 9%
• Protein 9%
• Time 8%
• Application 7%